When modeling covariate measurement error in regression, it is typically assumed that the measurement error acts in an additive or multiplicative manner on the true covariate value. However, such assumptions do not hold for the measurement error of sleep-disordered breathing (SDB). The true covariate is the severity of SDB, and the observed surrogate covariate is the number of breathing pauses ...

1309 SLEEP-DISORDERED BREATHING (SDB) IS A CONDITION CHARACTERIZED BY REPEATED BREATHING PAUSES AND REDUCED AIRFLOW DURING SLEEP, LEADING TO nocturnal arousals, unrefreshing sleep, and daytime sleepiness. SDB has been shown to be a contributing factor in diminished neurocognitive functioning.1-4 Specifically, within the spectrum of neurocognitive deficits, vigilance impairment or inability to s...

Adaptive servo-ventilation (ASV) is a form of non-invasive positive airway pressure (PAP) therapy that differs from other PAP devices. It includes features to overcome both obstructive and central sleep-disordered breathing (SDB) events. In the Treatment of Sleep-Disordered Breathing with Predominant Central Sleep Apnea by Adaptive Servo-Ventilation in Patients with Heart Failure (SERVE-HF) stu...

In recent years, there have been numerous reports addressing the relationship between sleep-disordered breathing (SDB) and hypertension (HTN). This study investigated the relationship between SDB and BP after controlling for age, gross obesity, and notably, antihypertensive medications. Sixty-seven men and women between 30 and 60 years of age and between 0.90 to 1.5 times ideal body weight were...

BACKGROUND Sleep disturbances such as sleep fragmentation, sleep disordered breathing (SDB), periodic limb movements (PLM), excessive daytime somnolence (EDS) and insomnia are prevalent in Parkinson's disease (PD). However, studies in the Asian population are limited. METHODS This was a cross-sectional study involving 46 Malaysians with PD using polysomnography (PSG) and standardized translat...

BACKGROUND AND PURPOSE Sleep-disordered breathing (SDB) negatively impacts stroke outcome. Near-infrared spectroscopy showed the acute cerebral hemodynamic effects of SDB. METHODS Eleven patients (7 men, age 61±13 years) with acute/subacute middle cerebral artery stroke (National Institutes of Health Stroke Scale score 10±7) and SDB (apnea-hypopnea index 32±28/hour) were assessed with nocturn...

The aim of the current study was to investigate the long-term impact of nocturnal noninvasive (positive-pressure) ventilation (NIV) on sleep, sleep-disordered breathing (SDB) and respiratory function in children and adolescents with progressive neuromuscular disorders (NMD). Thirty patients (12.3 +/- 4.1 yrs) with various inherited NMD were treated with NIV for ventilatory insufficiency (n=14) ...

AIMS To investigate blood pressure (BP) in children with sleep disordered breathing (SDB). METHODS BP was measured during single night polysomnography in 23 suspected SDB child patients with adenotonsillar hypertrophy, but without respiratory or heart failure, or coma. The age related changes of the observed BP were normalised to the BP index. The BP indices were examined in relation to SDB m...

OBJECTIVE The aim of the current study was to investigate whether changes in post- to pre-overnight sleep systolic blood pressure (SSBP) are associated with sleep respiratory disturbance, pro-inflammatory state, and metabolic situation in patients with sleep-disordered breathing (SDB). METHODS Anthropometry, sleep polysomnography, biochemical markers, and pre- and post-overnight sleep BP were...