نتایج جستجو برای: skin tumor

تعداد نتایج: 608087  

Journal: :Biological & pharmaceutical bulletin 2002
Masaki Baba Yongri Jin Atsuo Mizuno Hisaya Suzuki Yoshihito Okada Nobuo Takasuka Harukuni Tokuda Hoyoku Nishino Toru Okuyama

7-Isopentenyloxycoumarin (1) was isolated from Heracleum lanatum MICHX. (Umbelliferae). Compound 1 inhibited phospholipid metabolism and Epstein-Barr virus activation caused by a potent tumor promoter. In an in vivo experiment, topical application of 1 suppressed skin-tumor-formation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in 7,12-dimethylbenz[a]anthracene (DMBA) initiated mice. A...

Journal: :Cancer research 2013
Frank Rolfs Marcel Huber Florian Gruber Friederike Böhm Herbert J Pfister Valery N Bochkov Erwin Tschachler Reinhard Dummer Daniel Hohl Matthias Schäfer Sabine Werner

The antioxidant enzyme peroxiredoxin 6 (Prdx6) is a key regulator of the cellular redox balance, particularly under stress conditions. We identified Prdx6 as an important player in different phases of skin carcinogenesis. Loss of Prdx6 in mice enhanced the susceptibility to skin tumorigenesis, whereas overexpression of Prdx6 in keratinocytes of transgenic mice had the opposite effect. The tumor...

Journal: :Journal of Pathology and Translational Medicine 2018

Journal: :Cancer research 2001
A Mann K Breuhahn P Schirmacher A Wilhelmi C Beyer A Rosenau S Ozbek S Rose-John M Blessing

The role of granulocyte-macrophage colony-stimulating factor (GM-CSF) in tumorigenesis is complex. On the one hand, GM-CSF can promote tumor cell growth, survival, and even metastasis. On the other hand, it can stimulate tumor cell rejection. In skin, it is early expressed after topic application of tumor-promoting agents and therefore may be responsible for changes that correlate with skin tum...

Journal: :iranian journal of pathology 2013
alireza abdollahi sara sheikhbahaei somaye safinejad issa jahanzad

background and objectives: the most prevalent malignancy among women is known to be breast cancer (bc). several factors contribute to determining tumor prognosis and treatment strategies. in this study, the frequency and relevance of these factors are discussed. materials and methods: this cross-sectional study was carried out on 214 patients with bc, who referred to the cancer institute of im...

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