Introduction: Chronic rhinosinusitis (CRS) is a multifactorial disease. Allergies are considered a predisposing factor to CRS; however, this remains controversial. The objective of this research was to investigate the prevalence of co-morbidities and allergic reaction, and to specify the most common allergens in patients with confirmed CRS.   Materials and Methods: One hundred patients with sig...

Background Allergic rhinitis is one of the most common types of rhinitis. Allergen avoidance is the most important way of preventing this disease. The present study is carried out to determine the frequency of common aeroallergens in patients with allergic rhinitis in Gorgan city by skin prick test (SPT) reactivity. Materials and Methods  In this cross-sectional study 270 patients referring t...

Iran is the main producer of Saffron in the world and a great number of Khorasan (the largest province of Iran) are involved in growing this plant. Recently, saffron pollen has found great importance due to inducing allergic reactions. In this study, the prevalence and clinical symptoms of saffron pollen allergy and specific IgE level in saffron workers have been studied. For this purpose, 167 ...

Background: Immediate hypersensitivity reactions (IHR) to iodinated contrast media (ICM) have traditionally been considered nonallergic; however, the increasingly frequent reporting of positive skin test and basophil activation test results suggests a specifi c allergic mechanism in some patients. Skin tests have been proposed as a useful tool for diagnosis, although their sensitivity and predi...

BACKGROUND/PURPOSE The Irregularity Index is a measure of border irregularity from pigmented skin lesion images. The measure attempts to quantify the degree of irregularity of the structural indentations and protrusions along a lesion border. A carefully designed study has shown that the parameters derived from the Irregularity Index were highly correlated with expert dermatologists' notion of ...

sensitive skin is a frequently mentioned cosmetic complaint. addition of a biomimetic of neuromediator has recently appeared as a promising new way to cure skin care product problems. this study was aimed to assess the inhibitory effect of a biomimetic lipopeptide derived from proopiomelanocortin (bpomc) on capsaicin-induced sensory irritation in human volunteers and also to compare its protect...

OBJECTIVE Current guidelines recommend that egg-allergic patients receive an influenza vaccine skin test before the influenza vaccine. This study evaluated the safety of bypassing the skin test and administering graded doses of influenza vaccine to egg-allergic children. METHODS We conducted a retrospective chart-review study of egg-allergic patients aged 6 months to 18 years who received the...

INTRODUCTION The Montenegro skin test reaction and leishmaniasis lesions share fundamental characteristics of a delayed type hypersensitivity reaction. OBJECTIVES To determine whether the Montenegro skin test reaction (response to leishmanin) might approximate and thereby provide insight into the early inflammatory and immune response to Leishmania infection. MATERIALS AND METHODS We compar...

The total blood lymphocyte proliferation assay (TLP) was evaluated as a screening test for infection with Mycobacterium tuberculosis and was compared with the tuberculin (Mantoux) skin test. The results of TLP assays performed on 33 patients with tuberculosis and 37 non-tuberculous subjects were compared with results of skin tests performed in the previous year. There was a high correlation bet...