a 61-year-old female presented with complaints of fever, general weakness and hepatosplenomegaly. she had a history of nonfamilial peripheral neurofibromatosis diagnosed as von recklinghausen's disease since 30 years previous. physical examination was remarkable for skin colored cutaneous circumscribed nodules which appeared soft to the touch in both arms, the upper part of her abdomen, back, a...

Distant metastases are unusual at presentation and during the course of ovarian carcinoma. Skin metastases may be the first presenting sign of metastatic carcinoma of the ovary. Ovarian epithelial adenocarcinoma rarely metastasizes to the skin, and can be seen in less than 4% of patients. It usually presents as subcutaneous nodules and, less commonly, as inflammatory metastases, which mimic vir...

A total of 17 head of cattle presenting with typical "Elephant skin disease" were isolated from the rest of the herd within a beef ranch for further clinical observation. On physical examination, all the animals had characteristic sclero-conjunctival cysts of Besnoitia besnoiti. In addition, some of the animals had characteristic skin nodules on the legs, ears and back. Histological examination...

The Ehlers-Danlos syndrome is a congenital abnormality of the skin, of which the following may be considered the chief characteristics: (1) Abnormal friability of the skin and subcutaneous tissue; (2) loose and hyperelastic skin; (3) hyperextensibility of joints; (4) the presence of nodules of various types in the skin ; (5) well-marked epicanthic folds. The clinical picture is not invariably c...

Cutaneous involvement is frequent in adult T-cell leukaemia/lymphoma (ATLL), a peripheral T-cell neoplasm caused by human T-cell lymphotropic virus type I (HTLV-I). Patients with ATLL manifest different types of skin lesions, including nodules, plaques, ulcers, erythroderma and purpura. It has been reported that this type of skin eruption is an independent prognostic factor for ATLL. We report ...

The association of leprosy and cutaneous tuberculosis has been reported rarely. Though cross-immunity may exist between these two mycobacterial infections, tuberculosis can occur throughout the spectrum of leprosy. We report a case of lepromatous leprosy with Type II reaction, with tuberculosis verrucosa cutis (TVC). The patient presented with multiple skin-coloured tender nodules of variable s...