The association of pemphigus and thymoma is real, although rare. We report a 73-year-old woman presenting with cutaneous bullac and erosions superimposed on erythematous and urticarial plaques, and a positive Nikolsky sign. She. had a large mediastinal mass that proved to be a benign thymoma. Her skin biopsy and direct immunofluorescence test were suggestive of superficial pemphigus.

In the Bio-medical environment, for the analysis of abnormality detection in the skin including skin cancer in the epidermal layer, the traditional method used is biopsy procedure. The obtained biopsy specimens are processed by various methods viz, various orders of harmonic generations enumerate certain results resulting in the chances of some unexpected infections. Later on to overcome these ...

generalized lipodystrophy is a rare disorder in children characterized by absence of subcutaneous adipose tissue. we evaluated 10 patients with generalized lipodystrophy by skin and liver biopsy. eight patients with steatohepatitis and cirrhosis were treated with ursobile (uorsodeoxycholic acid) and vitamin e. in follow-up, serum triglyceride level was decreased.

we presents an infant with several indurated plaques and nodules scattered on her body. she was brought to the hospital because of fever, runny nose and cough from one month ago. during the examination and investigation the plaques and nodules grabbed the attention of the clinicians and the skin biopsy and other lab works revealed the diagnosis of congenital leukemia.

atopic dermatitis (ad) is a heterogeneous disease with regard to clinical phenotype and natural history. we investigated t cell subtypes and cytokine responses in peripheral blood and skin lesions of ad patients with various sensitivities. immunological studies were performed in 27 subjects: 9 house dust mite (hdm)-sensitized; 6 subjects with sensitizations other than hdm; 7 non-allergic ad pat...

BACKGROUND UV radiation induces damage to human skin. Protection of skin by an oral photoprotective agent would have substantial benefits. Objective We investigated the photoprotective effect of oral administration of an extract of the natural antioxidant Polypodium leucotomos (PL). METHODS A total of 9 healthy participants of skin types II to III were exposed to varying doses of artificial U...

The incidence of malignant melanoma is increasing every year. Revealing melanoma in situ on time is increasing good prognosis of these patients. To evaluate the role of digital epiluminescence microscopy (DELM) in the differential diagnosis of cutaneous pigmented lesions and to improve the early diagnosis of melanoma in situ, 8384 pigmented lesions from 3927 consecutive patients were evaluated ...

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis has been recently recognized in Graves' disease patients treated with antithyroid drugs. We describe the case of an 18-year-old girl who developed antimyeloperoxidase ANCA (MPO-ANCA)-positive vasculitis manifesting as a skin lesion and hemoptysis with hypoxic respiratory failure after taking methimazole. An open lung biopsy was co...

Lafora’s disease (lafora body disease) a rarely seen and progressive disease characterised by mental decline, myoclonus and seizures. Definitive diagnosis is made with skin biopsy showing typical spherical pas positive inclusion bodies. We present a case who had myoclonus, generalized seizures and dementia, diagnosed lafora‘s body disease, confirmed by skin biopsy. Magnetic resonance spectrosco...