For decades, single case experimental designs (SCED) have been used to examine the effectiveness of clinical and educational interventions and have contributed significantly to the development of the general lines of clinical and educational researches. In recent years, with the movement of evidence-based methods, the methodology of single case experimental designs has also evolved. Visual anal...

Background and Aims: In this in-vitro study, the effect of multiple adhesive coating on the microshear bond strength of composite to dentin and surface microhardness of dentin after treatment with four adhesives (One Step Plus, One Step, Single Bond, Single Bond 2) were evaluated. Materials and Methods: One hundred intact human molars were cut to obtain disks of dentin having 2 mm thickness. F...