prions are unprecedented infectious pathogens that cause a group of invariably fatal neurodegenerative disease by an entirely novel mechanism. the conformational change in prion proteins results in a change from a predominantly α-helical protein to a β-sheet form, which causes scrapie in sheep and goat. the present study was carried out to identify polymorphisms of the prion protein gene (prp) ...

despite existing various integer programming for sequencing problems, there is not enoughinformation about practical values of the models. this paper considers the problem of minimizing maximumlateness with release dates and presents four different mixed integer programming (mip) models to solve thisproblem. these models have been formulated for the classical single machine problem, namely sequ...

abstract background: in recent years, laparoscopic sleeve gastrectomy (lsg) has become more acceptable for obese patients. single-port sleeve gastrectomy (spsg) is more popular since each abdominal incision carries the risk of bleeding, hernia, and internal organ injury as well as exponentially affecting cosmesis. this cross-sectional study aimed at comparing multi-port sleeve gastrectomy (mpsg...

introduction the aim of this study was toinvestigate the sterilization potential of atmospheric pressure plasma jet (appj) and interactions of this technology with double-stranded dna using the polymerase chain reaction (pcr) and single-strand conformation polymorphism (sscp) techniques. materials and methods the plasma jet was produced through a high voltage sinusoidal power supplyusing a mixt...

ultrasonic vibration assisted single point incremental forming (uvaspif) process is an attractive and adaptive method in which a sheet metal is gradually and locally formed by a vibrating hemispherical-head tool. the ultrasonic excitation of forming tool reduces the average of vertical component of forming force and spring-back rate of the formed sample. the spring-back phenomenon is one of the...

to simulate a new economical architecture for pem fuel cell and investigate the effectiveness of the introduced structure on the performance, computational fluid dynamics (cfd) code is used to solve the equations for a single domain of the cell namely: the flow field, the mass conservation, the energy conservation, the species transport, and the electric/ionic fields under the assumptions of st...

the problem of scheduling with multi agent has been studiedfor more than one decade and significant advances have been madeover the years. however, most work has paid more attention to the conditionthat machines are available during planning horizon. motivatedby the observations, this paper studies a two-agent scheduling modelwith multiple availability constraint. each agent aims at minimizing ...

tumor necrosis factor alpha-inducible protein 3 (tnfaip3) gene polymorphisms have been reported to be associated with the susceptibility to several immune-related diseases. here we investigated the effect of tnfaip3 gene polymorphisms on the risk of allergic rhinitis (ar) in a chinese han population. the case-control study included 540 ar patients and 524 healthy controls. genotyping for tnfaip...

ankylosing spondylitis (as) is an inflammatory arthritis, which affects mainly spine and sacroiliac joints. according to recent studies, erap1 is the second most common candidate gene for  as susceptibility after hla-b27. the  aim of this study was to  determine the association of erap1 gene polymorphisms with as in iranian population. the study group comprised 387 iranian as patients and 316 h...