Mismatch between areas of reduced myocardial blood flow (MBF) and reduced myocardial innervation (’defect’ areas) may be used to predict ventricular arrhythmias. The presence of a mismatch zone can be derived from a combined protocol consisting of both an MBF and [C]-meta-hydroxyephedrine ([C]HED) scans. The rate of influx of [C]HED from blood to myocardium (K1) is proportional to MBF and could...

Background Myocardial CT perfusion is a relatively new technique which enables the assessment of perfusion deficits through first pass imaging in combination with pharmacological stress. Comparison of CT and MR perfusion has been limited and in-vivo assessment is affected by physiological variability, acquisition timing during firstpass contrast perfusion and parameter selection. We utilized a ...

to make an accurate estimation of the uptake of radioactivity in an organ using the conjugate view method, corrections of physical factors, such as background activity, scatter, and attenuation are needed. the aim of this study was to evaluate the accuracy of four different methods for background correction in activity quantification of the heart in myocardial perfusion scans. the organ activit...

Cardiovascular Magnetic Resonance (CMR) is recognised as a valuable clinical tool which in a single scan setting can assess ventricular volumes and function, myocardial fibrosis, iron loading, flow quantification, tissue characterisation and myocardial perfusion imaging. The advent of CMR using extrinsic and intrinsic contrast-enhanced protocols for tissue characterisation have dramatically cha...

Although a number of imaging modalities are available to non-invasively evaluate patients with suspected or known coronary artery disease (CAD), myocardial perfusion scintig-raphy (MPS) with single photon emission computed tomog-raphy (SPECT) has been the workhorse for this purpose for over decades [1]. Notwithstanding its high sensitivity to detect ischaemia (85–90 %), a caveat of a normal per...

The aim of this study was to determine the accuracy of fuzzy rule-based classification that could noninvasively predict CAD based on myocardial perfusion scan test and clinical-epidemiological variables. This was a cross-sectional study in which the characteristics, the results of myocardial perfusion scan (MPS), and coronary artery angiography of 115 patients, 62 (53.9%) males, in Mazandaran H...

BACKGROUND Dyspnea is a complex system with multiple etiologies, including myocardial ischemia ("anginal equivalent"). Few studies have examined the utility of stress testing to detect coronary artery disease in this setting. The purpose of this study was to examine the prevalence, severity, and prognostic value of perfusion defects detected by stress single photon emission computed tomography ...

background: standard methods for the measurement of myocardial perfusion are invasive and require cardiac catheterization or the use of radioisotope dyes. the coronary sinus blood flow (csbf) is an appropriate criterion for the efficacy of myocardial perfusion. this study sought to measure csbf via transthoracic echocardiography (tte) in patients with acute myocardial infarction (ami) and to as...