Experiments in rabbits were designed to test the two unproven assumptions of the hypothesis proposed in the companion paper (1): that Original Antigenic Sin is fundamentally a restricted anamnestic response, and that there exists a trapping mechanism capable of deflecting antigen from one kind of cell and guiding it to another. It is shown that whole-body X-irradiation, sufficient to abolish pr...

Cytokinesis in fission yeast is controlled by the Septation Initiation Network (SIN), a protein kinase signaling network using the spindle pole body as scaffold. In order to describe the qualitative behavior of the system and predict unknown mutant behaviors we decided to adopt a Boolean modeling approach. In this paper, we report the construction of an extended, Boolean model of the SIN, compr...

The fission yeast septation initiation network (SIN) triggers the onset of septum formation and cytokinesis. SIN proteins signal from the spindle pole body (SPB), to which they bind in a cell cycle-dependent manner, via the scaffold proteins sid4p and cdc11p. cdc11p becomes hyperphosphorylated during anaphase, when the SIN is active. We have investigated the phosphorylation state of cdc11p duri...

We derive the renormalization group equations for the neutrino masses and mixing angles in explicit form and discuss the possible classes of their solutions. We identify fixed points in the equations for mixing angles, which can be reached during the evolution for several mass patterns and give sin 2θsol = sin 2 2θatm sin 2 θ3/(sin 2 θatm cos 2 θ3 + sin 2 θ3) , consistently with the present exp...

with initial conditions r(0) = do and ṙ(0) = vo. If the system is un-damped (C = 0N×N), the free response of the system will not decay with time, and a suitable trial solution to the differential equation (1) is r(t) = r̄ sin(ωnt), where r̄ is a constant vector of dimension N . Differentiating r(t) twice, r̈(t) = −ω2 nr̄ sin(ωnt), and substituting the trial solution into equation (1) we obtain − ω2...

Measles remains a major worldwide problem partly because of difficulties with vaccination of young infants. New vaccine strategies need to be safe and to provide sustained protective immunity. We have developed Sindbis virus replicon particles that express the measles virus (MV) hemagglutinin (SIN-H) or fusion (SIN-F) proteins. In mice, SIN-H induced high-titered, dose-dependent, MV-neutralizin...

We show that the lattice of all ideals of a ring $R$ can be embedded in the lattice of all its fuzzyideals in uncountably many ways. For this purpose, we introduce the concept of the generalizedcharacteristic function $chi _{s}^{r} (A)$ of a subset $A$ of a ring $R$ forfixed $r , sin [0,1] $ and show that $A$ is an ideal of $R$ if, and only if, its generalizedcharacteristic function $chi _{s}^{...

Aim: To assess the surface topography and chemical composition of three brands of as-received mini-implants (SIN®, Morelli®, and Conexao®). Methods: Twelve mini-implants of each brand were analyzed by scanning electron microscopy and energy dispersive X-ray (EDX). Results: There was no significant differences among SIN®, Morelli®, and Conexao® mini-implants comparing their surface topography by...

(Def. 2) cosec = 1 the function sin . For simplicity, we follow the rules: x, a, b, c are real numbers, n is a natural number, Z is an open subset of R, and f , f1, f2 are partial functions from R to R. One can prove the following propositions: (1) If (the function cos)(x) 6= 0, then sec is differentiable in x and (sec)′(x) = (the function sin)(x) (the function cos)(x)2 . (2) If (the function s...