We present a compiler that translates a multi-agent systems specification given in the formalism of Interpreted Systems into an SMV program. We show how an SMV model checker can be coupled with a Kripke model editor (Akka) to allow for the mechanical verification of epistemic properties of multi-agent systems. We apply this methodology to the verification of a communication protocol — the dinin...

background and aims. statins, the mevalonate pathway inhibitors, have effects on bone formation in vitro and in vivo. the aim of the present study was to investigate whether injection of statins could lead to ectopic bone formation in rats. materials and methods. a single dose (0.5 mg) of simvastatin, atrovastatin, lovastatin and polyethylene glycol (control material) were injected into four qu...

BACKGROUND Previous attempts to provide right heart assistance with skeletal muscle ventricles (SMVs) have been frustrated by the low preload supplied by the systemic venous blood pressure. In the present study, right ventricular pressure was exploited to provide more optimal preload, the SMV being connected by valved conduits between right ventricular free wall and the main pulmonary artery. ...

The usefulness of endoscopic ultrasonography (EUS) in the evaluation of rectal varices (RV) was determined in 50 patients with portal hypertension (PH) and 25 PH-free controls. F(1) and F(2) varices and angiectasia were specific for the PH group as evaluated by endoscopy, but there was no difference between the PH and the control groups with respect to the frequency of blue vein. The detection ...

BACKGROUND Outcome data on simeprevir and sofosbuvir (SMV+SOF) in patients with liver transplantation (LT) with hepatitis C virus genotype 1 (HCV-1) are limited with individual studies having a small sample size and limited SVR12 (sustained virological response) data. Our goal was to perform a meta-analysis to study the outcome of SMV+SOF±ribavirin (RBV) in recipients with LT. METHODS In Apri...

We present Selective Multi-Versioning (SMV), a new STM that reduces the number of aborts, especially those of long read-only transactions. SMV keeps old object versions as long as they might be useful for some transaction to read. It is able to do so while still allowing reading transactions to be invisible by relying on automatic garbage collection to dispose of obsolete versions. SMV is most ...

Microsatellites (MST), tandem repeats of 1-6 nucleotide motifs, are mutational hot-spots with a bias for insertions and deletions (INDELs) rather than single nucleotide polymorphisms (SNPs). The majority of MST instability studies are limited to a small number of loci, the Bethesda markers, which are only informative for a subset of colorectal cancers. In this paper we evaluate non-haplotype al...

Each phase of the HCV replication cycle can represent a therapy target. In fact, SIMEPREVIR (SMV) acts as NS3/4A protease inhibitor (PI); its efficacy is, however, reduced in HCV1a patients characterized by NS3Q80K polymorphism. The aim of this work was to design a genotypic analysis of NS3 protease in order to characterize viral quasispecies in HCV 1a patients before starting the SMV therapy. ...