The aim of this study was to evaluate the efficacy and safety of an anti-hypercholesterolemic agent containing Berberis aristata, Silybum marianum and monacolin K and KA in a sample of Caucasian patients at low cardiovascular risk according to Framingham score. The primary outcome was to evaluate the effects of this nutraceutical combination on lipid profile; the secondary outcome was to evalua...

This work is devoted to the study of effect Ilex paraguariensis decoction for energy and carbohydrate metabolism in conditions increased physical activity, analysis stabilisation possibilities liver injury lipid peroxidation markers rats an experimental model chronic alcohol intoxication. It’s established that I. exhibits antioxidant hepatoprotective effects with alcoholic liver, comparable act...

In order to respond to the basic requirements of food and pharmaceutical industries, to reduce or eliminate organic solvent residues in the final products, several extraction techniques were tested from the standpoint of performance, with low energy consumption. The aim of this study was to determine biological activities such as antioxidant and antiproliferative activities of flavonolignans fr...

Seeds of Silybum marianum which have been used to treat liver diseases have an active component called silymarin. Hairy root cultures of S. marianum could be able to produce silymarin. There is evidence that the use of elicitors has been an important strategy for improving the production of secondary metabolites. Elicitation is an interesting topic to investigate cell signaling pathway in secon...

This study was performed to investigate the effect of Ag+ as an elicitor on the activity of antioxidant enzymes, content of H2O2, accumulation of total tocopherol and antioxidant activity in hairy root cultures of Silybum marianum (L.) Gaertn. The hairy roots were treated with 2 mM Ag+. The treated and non-treated hairy roots were harvested in the same time and data on H2O2 content, DPPH, tocop...