BACKGROUND AND PURPOSE MR imaging of the salivary glands has been applied to the diagnosis of Sjogren's syndrome; however, the diagnosis remains qualitative. We sought to establish and evaluate quantitative MR imaging criteria for the diagnosis of Sjogren's syndrome. METHODS MR imaging with a 47-mm microscopy coil was performed in 83 patients with xerostomia (55 patients with Sjogren's syndro...

The regenerating gene (Reg) was isolated originally as a gene specifically over-expressed in regenerating pancreatic islets and constitute a growth factor family. Reg gene product (Reg) is important in the pathophysiology of various human inflammatory diseases. Recently, the possible involvement of human REG in the regeneration of salivary ductal epithelial cells of patients with primary Sjögre...

Sjögren's syndrome is an autoimmune exocrinopathy which manifests itself with dryness of the eyes and the oral cavity. These symptoms comprise a so-called sicca syndrome (xerostomia and xerophthalmia). Two forms of this disease may be distinguished: primary Sjögren's syndrome which affects salivary glands and secondary Sjögren's syndrome with other autoimmune diseases present such as rheumatoid...

To cite: Tsuchida Y, Sumitomo S, Fujio K, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2015-214006 DESCRIPTION A 28-year-old Japanese woman presented with subcutaneous nodules on the extensor surface of her elbows and knees, which had been present for 6 years. Radiographs of the knees showed numerous calcifications, up to 13 mm in diameter, in the subcu...

IMPORTANCE Nodular fasciitis is a rare benign tumor that can present in the head and neck in children. A better understanding of this rare condition is critical to optimize management. OBJECTIVE To review the presentation, evaluation, diagnosis, and management of pediatric nodular fasciitis of the head and neck. DESIGN, SETTING, AND PARTICIPANTS Retrospective review of all patients treated ...

From time to time a child is seen with swelling of the parotid gland in whom mumps is diagnosed, yet the parent states that the patient has had that disase several times before. Due largely to the work of Payne (1933, 1938, 1940) the condition of recurrent parotid swelling has been defined as a clinical entity, but most of the published accounts refer to adults. The disease, however, is by no m...

From time to time a child is seen with swelling of the parotid gland in whom mumps is diagnosed, yet the parent states that the patient has had that disase several times before. Due largely to the work of Payne (1933, 1938, 1940) the condition of recurrent parotid swelling has been defined as a clinical entity, but most of the published accounts refer to adults. The disease, however, is by no m...