Sialoliths are calcified concrements that develop in the parenchyma or ducts of the salivary glands and are among the most common causes of obstructive sialadenitis. The majority of sialoliths (84%) are located in the submandibular gland, particularly (90%) in the Wharton’s duct. 1 Sialoliths become symptomatic when they block salivary flow or cause an infection. Most patients present with swel...

PURPOSE To evaluate nuclear NF-κ B translocation in minor salivary glands (mSG) of human primary Sjögren Syndrome (pSS). METHODS Lip biopsies' mSG were done in 24 female patients with pSS from the Rheumatology Service of Rivadavia Hospital. Glands were stained with H&E and immunostained for NF-κ B. Specimens were classified according to the Chisholm and Masson score. RESULTS The biopsies (H...

OBJECTIVES To assess the efficacy of the sialoendoscopic technique for treatment of inflammatory salivary gland diseases. This report documents the authors' long-term experience with sialoendoscopy and discusses the long-term results of the procedure, technical issues, and varieties that they have utilized, as well as the advantages and limitations of this modality. STUDY DESIGN Retrospective...

B cell-activating factor belonging to the TNF family (BAFF) is a B cell survival factor required for B cell maturation. BAFF transgenic (Tg) mice develop autoimmune disorders characterized by autoantibody production, which leads to nephritis and salivary gland destruction (sialadenitis), features reminiscent of systemic lupus erythematosus and Sjögren's syndrome (SS), respectively. Disease in B...

Title Macrophage-dominant sialadenitis in human T-cell leukemia virus type Iassociated myelopathy after living-donor liver transplantation. Author(s) Nakamura, Hideki; Ichikawa, Tatsuki; Nakamura, Tatsufumi; Kawakami, Atsushi; Iwamoto, Naoki; Matsuzaki, Toshihisa; Miyaaki, Hisamitsu; Yamasaki, Satoshi; Ida, Hiroaki; Eguchi, Susumu; Hayashi, Tomayoshi; Nakao, Kazuhiko; Kanematsu, Takashi; Eguchi...

With an incidence of 1.2% in the general population, obstructive sialadenitis, with or without sialolithiasis, represents the most common inflammatory disorder of the major salivary glands.1,2 Sialoliths most commonly occur in the submandibular gland, outnumbering the parotid gland by approximately 4:1, while they occur in the sublingual gland in just 0-6.4% of cases.3,4,5 Because the sublingua...

A 15-year-old boy presented with swelling in the submandibular region. X-ray of the swollen part showed faint radio opaque shadow. A provisional diagnosis of sialadenitis with sialolithiasis was made. Excised mass was reported histopathologically as plexiform neurofibroma of submandibular salivary gland.Plexiform neurofibroma of the salivary gland is a rare benign tumor often present in the par...