نتایج جستجو برای: shv بتالاکتاماز

تعداد نتایج: 1355  

2010
Caio Fernando de Oliveira Adenilde Salla Valéria Maria Lara Alexandre Rieger Jorge André Horta Sydney Hartz Alves

The emergence of Extended-Spectrum Beta-Lactamase (ESBL)-producing microorganisms in Brazilian hospitals is a challenge that concerns scientists, clinicians and healthcare institutions due to the serious risk they pose to confined patients. The goal of this study was the detection of ESBL production by clinical strains of Escherichia coli and Klebsiella sp. isolated from pus, urine and blood of...

Journal: :Antimicrobial agents and chemotherapy 1994
Y Cheng M Chen

Resistance to ceftazidime, detected in isolates of Escherichia coli 5518 and Enterobacter gergoviae 3773 from our hospital, was transferred, together with resistance to aminoglycosides, trimethoprim, sulfonamide, and other beta-lactam antibiotics, by conjugation to E. coli JP559. Both E. coli transconjugants were resistant to ampicillin, all cephalosporins, and aztreonam but remained susceptibl...

2015
Nikhil P. Krishnan Nhu Q. Nguyen Krisztina M. Papp-Wallace Robert A. Bonomo Focco van den Akker Israel Silman

β-Lactamase inhibition is an important clinical strategy in overcoming β-lactamase-mediated resistance to β-lactam antibiotics in Gram negative bacteria. A new β-lactamase inhibitor, avibactam, is entering the clinical arena and promising to be a major step forward in our antibiotic armamentarium. Avibactam has remarkable broad-spectrum activity in being able to inhibit classes A, C, and some c...

2014
Elizabeth A. Rodkey Marisa L. Winkler Christopher R. Bethel Sundar Ram Reddy Pagadala John D. Buynak Robert A. Bonomo Focco van den Akker

β-Lactamases are the major reason β-lactam resistance is seen in Gram-negative bacteria. To combat this resistance mechanism, β-lactamase inhibitors are currently being developed. Presently, there are only three that are in clinical use (clavulanate, sulbactam and tazobactam). In order to address this important medical need, we explored a new inhibition strategy that takes advantage of a long-l...

کسری کرمانشاهی, روحا, گلعلی پور, مسعود, کیوانی امینه, حسین ,

سابقه و هدف: استافیلوکوکوس آرئوس گونه شاخص و بیماریزای انسانی می باشد. چندین عامل حدت در این باکتری مشخص گردیده است که پروتئین A و بتالاکتاماز مهمترین عوامل ویرولانس آن می باشند. هدف مطالعه بررسی ارتباط بین دو عامل حدت (بتالاکتاماز و پروتئین A) در این میکروارگانیسم بوده است. مواد و روش ها: مقاومت به بتالاکتام های حساس به بتالاکتاماز (پنی سیلین G، سفازولین، سفالوتین) و مقاوم به بتالاکتاماز (متی ...

Journal: :Antimicrobial agents and chemotherapy 2009
Hanna E Sidjabat David L Paterson Jennifer M Adams-Haduch Lindsay Ewan Anthony W Pasculle Carlene A Muto Guo-Bao Tian Yohei Doi

A combination of phenotypic and genotypic methods was used to investigate 70 unique Escherichia coli clinical isolates identified as producing extended-spectrum beta-lactamases (ESBLs) at a medical center in Pittsburgh, PA, between 2007 and 2008. Fifty-seven isolates (81%) produced CTX-M-type ESBLs, among which CTX-M-15 was predominant (n = 46). Isolates producing CTX-M-2, -9, -14, and -65 were...

Journal: :Journal of virology 2001
T Pfister E Wimmer

Southampton virus (SHV) is a member of the Norwalk-like viruses (NLVs), one of four genera of the family Caliciviridae. The genome of SHV contains three open reading frames (ORFs). ORF 1 encodes a polyprotein that is autocatalytically processed into six proteins, one of which is p41. p41 shares sequence motifs with protein 2C of picornaviruses and superfamily 3 helicases. We have expressed p41 ...

2014
Zahra Meshkat Nafiseh Izadi Mahboubeh Naderi Nasab Elnaz Harifi Mood

Background & Objectives: Extended-spectrum-B-lactamase (ESBL)-producing strains of Klebsiella Pneumonia are an important cause of many serious infections in hospitalized and nonhospitalized patients and delayed treatment of these infections in crease chance of death in patients. This study was performed to determine the prevalence of ESBL-producing K. Pneumonia and to evaluate the frequency of ...

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