Exon-shuffled constructs between mouse (IA beta b) and human (DR3 beta) class II beta chains were made to study the interaction sites between CD4 and major histocompatibility complex (MHC) class II molecules, and to determine whether a species barrier is involved. The overall structure and the peptide binding groove appeared to be unaffected by the exon shuffling procedure as determined by mono...

Quasi-random number sequences have been used extensively for many years in the simulation of integrals that do not have a closed-form expression, such as Mixed Logit and Multinomial Probit choice probabilities. Halton sequences are one example of such quasi-random number sequences, and various types of Halton sequences, including standard, scrambled, and shuffled versions, have been proposed an...

The apparent “boosted mobility” observed by Wang et al . (Reports, 31 July 2020, p. 537) is the result of a known artifact. When signal intensities are changing during nuclear magnetic resonance (NMR) diffusion measurement for reasons other than diffusion, use monotonically increasing gradient amplitudes produces erroneous coefficients. We show that no boosted molecular mobility when shuffled a...

The problem of accurate determination of the position, orientation and width of involute spur gear teeth using a single front-lit image is addressed. The information is used to compute global measures of tooth concentricity and pitch variations across a gear wheel. The approach is based on the use of specialised filters which make maximum use of the grey level information available in the image...

Abstract The use of machine learning in automatic speaker identification and localization systems has recently seen significant advances. However, this progress comes at the cost using complex models, computations, increasing number microphone arrays training data. Therefore, work, we propose a new end-to-end model based on simple fully connected deep neural network (FC-DNN) just two input micr...

measurement of magnitude and frequency of the voltage flicker is very important for monitoring andcontrolling voltage flicker efficiently to improve the network power quality. this paper presents twonew methods for measurement of flicker signal parameters using shuffled frog leaping algorithm(sfla) and imperialist competitive algorithm (ica). this paper estimates fundamental voltage andflicker ...