نتایج جستجو برای: shla

تعداد نتایج: 135  

2012
Pietra Graebin Tiago D Veit Clarice S Alho Fernando S Dias José AB Chies

INTRODUCTION Critically ill patients are characterized as individuals hospitalized in the Intensive Care Unit (ICU) and can evolve to sepsis, septic shock or even death. Among others, genetic factors can influence the outcome of critically ill patients. HLA-G is a non-classical class Ib molecule that has limited protein variability, presenting seven isoforms generated by alternative splicing, a...

Journal: :The Open Rheumatology Journal 2008
Martin Feuchtenberger Sabine Müller Petra Roll Anne Waschbisch Arne Schäfer Christian Kneitz Heinz Wiendl Hans-Peter Tony

OBJECTIVES Transient B cell depletion with the monoclonal anti-CD20 antibody rituximab has shown favourable clinical responses in patients with rheumatoid arthritis (RA). Recently a characteristic regeneration pattern of B cell subpopulations has been reported. However, little is known about the impact of B-cell depletion on peripheral T cells in particular regulatory T cells. MATERIALS AND M...

2017
Ramanathan Srinivasan Ramar Mohankumar Arunachalam Kannappan Veeramani Karthick Raja Govindaraju Archunan Shunmugiah Karutha Pandian Kandasamy Ruckmani Arumugam Veera Ravi

Quorum Sensing (QS) mechanism, a bacterial density-dependent gene expression system, governs the Serratia marcescens pathogenesis through the production of virulence factors and biofilm formation. The present study demonstrates the anti-quorum sensing (anti-QS), antibiofilm potential and in vivo protective effect of phytol, a diterpene alcohol broadly utilized as food additive and in therapeuti...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Heather D Hickman Jonathan W Yewdell

T he class I MHC-CD8–T-cell immunosurveillance system constitutes a major component of the adaptive immune system in mammals and other jawed vertebrates. All cell types (except erythrocytes) constitutively express MHC class I molecules, which are comprised of a type I membraneanchored glycoprotein (heavy chain) noncovalently bound to β2-microglobulin (β2m) and a peptide typically of 8–11 residu...

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