Shigellosis is one of the leading causes of diarrhea worldwide with more than 165 million cases annually. Hence, a vaccine against this disease is a priority, but no licensed vaccine is still available. Considering target population as well as intrinsic risks of live attenuated vaccines, non-living strategies appear as the most promising candidates. Remarkably, the preservation of antigenic pro...

Acute infectious diarrhea (AID) can cause severe diarrhea which is called shigellosis. Shigella spp. are a group of pathogenic bacteria transmitted through contaminated food [1, 2]. This group of bacteria causes about 165 million cases of diarrhea each year, out of which 163 million occur in developing countries, and 1.5 million in industrialized nations [3]. Shigella species are mainly transmi...

Shigellosis presents with varied clinical features are dictated by the species involved, virulence factors of the strain, and the host immune status. We studied the species, virulence genes, and antibiotic susceptibility pattern of the Shigella strains isolated from 33 children aged less than 12 years, with clinical features of shigellosis. Identification and antibiotic sensitivity of Shigella ...

During 2000-2012, U.S. Air Force Public Health Offices reported 3,429 cases of gastrointestinal infection (GI) diagnosed at Air Force medical treatment facilities. The four most commonly reported specific etiologies of GIs accounted for 86.7% of all GI cases (n=2,972). Salmonellosis accounted for 41.4% (n=1,420) of all cases. The next most commonly reported events were associated with Campyloba...

OBJECTIVE To evaluate the distribution and susceptibility to antimicrobials of Shigella isolated from children with acute diarrhea and without diarrhea in Teresina, state of Piauí, Brazil. METHODS Four hundred children aged up to 60 months were studied. Stools were collected from all the patients between January 2004 and August 2007. Shigella was identified by conventional methods and antibio...

In Japan, the incidence of Shigellosis is low at approximately 150 cases per year, with the majority of these being imported, mainly from Asia. Sporadic domestic occurrences are also reported, the majority of which absent epidemiological association. We report a case of gastroenteritis caused by Shigella flexneri in a 60-year-old Japanese female who recovered fully following treatment with levo...

Anti-WNV IgG was more often detected in participants in the 20to 29-year age group (odds ratio [OR] 4.23, 95% confidence interval [CI] 1.04–16.02, p = 0.03) and in persons who reported frequent mosquito bites (OR 8.62, 95% CI 0.44–169, p = 0.08). IgG-positive persons were equally divided by sex. No significant differences were found between antibody-positive or antibody-negative persons with re...

Introduction: Shigellosis is a contagious disease with acute symptoms. Delay in detecting the disease transmission way would lead to rapid spread among the community, like what happened in Isfahan Provincein April 2015. The study aimed at evaluating the Shigella bacteria transmission medium in the outbreak that occurred in Isfahan Province, Iran. Methods: Due ...

Shigella sonnei has become the most frequently reported cause of shigellosis in the United States. Since Shigella subgroup D has no other serotypes, colicin production has been used as a basis for differentiating and identifying epidemiologically related strains. The results of colicin typing 115 cultures of S. sonnei from eight outbreaks of shigellosis occurring in widely separated regions of ...