نتایج جستجو برای: shiga toxin 2

تعداد نتایج: 2566816  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1987
S B Calderwood F Auclair A Donohue-Rolfe G T Keusch J J Mekalanos

We have determined the nucleotide sequence of the sltA and sltB genes that encode the Shiga-like toxin (SLT) produced by Escherichia coli phage H19B. The amino acid composition of the A and B subunits of SLT is very similar to that previously established for Shiga toxin from Shigella dysenteriae 1, and the deduced amino acid sequence of the B subunit of SLT is identical with that reported for t...

Journal: :Applied and environmental microbiology 2012
Maite Muniesa Jens A Hammerl Stefan Hertwig Bernd Appel Harald Brüssow

In 2011, Germany experienced the largest outbreak with a Shiga toxin-producing Escherichia coli (STEC) strain ever recorded. A series of environmental and trace-back and trace-forward investigations linked sprout consumption with the disease, but fecal-oral transmission was also documented. The genome sequences of the pathogen revealed a clonal outbreak with enteroaggregative E. coli (EAEC). So...

2014
Rebecca L. Lindsey Eija Trees Scott Sammons Vladimir Loparev Mike Frace Nancy Strockbine Ashley L. Sabol Evan Sowers Devon Stripling Haley Martin Kristen Knipe Lori Rowe Peter Gerner-Smidt

Shiga toxin-producing Escherichia coli (STEC) is an important food-borne pathogen. Here, we report the draft whole-genome sequences of nine STEC strains isolated from clinical cases in the United States. This is the first report of such information for STEC of serotypes O69, H11, O145:H25, O118:H16, O91:H21, O146:H21, O45:H2, O128:H2, and O121:H19.

2015
Rebecca L. Lindsey Kristen Knipe Lori Rowe Lisley Garcia-Toledo Vladimir Loparev Phalasy Juieng Eija Trees Nancy Strockbine Devon Stripling Peter Gerner-Smidt

Shiga toxin-producing Escherichia coli (STEC) is an important foodborne pathogen. Here, we report complete whole-genome sequences for two STEC strains of serotypes O119:H4 and O165:H25 isolated from clinical cases in the United States.

Journal: :Journal of medical microbiology 2007
Thomas P Griener George L Mulvey Paola Marcato Glen D Armstrong

Shiga toxins (Stx1 and Stx2) are responsible for initiating haemolytic uraemic syndrome, a serious extraintestinal complication caused by enterohaemorrhagic Escherichia coli O157 : H7 infection in humans. Shiga toxins are classical AB(5)-type exotoxins, consisting of a globotriaosylceramide (Gb(3))-binding B subunit pentamer and an enzymic A subunit. It is demonstrated in this study that Stx2 b...

Journal: :iranian journal of microbiology 0
pantea mohammadi medical biology research center, university of medical sciences, kermanshah, iran. ramin abiri department of microbiology, faculty of medicine, university of medical sciences, kermanshah, iran. mansour rezaei department of statistics and epidemiology, faculty of health, university of medical sciences, kermanshah, iran. siavosh salmanzadeh-ahrabi department of microbiology, alzahra university, tehran, iran.

background and objectives: infectious diarrhoeal diseases are great problem throughout the world and are responsible for considerable morbidity and mortality. shiga toxin-producing escherichia coli (stec) is a major cause of gastroenteritis that may be complicated by hemorrhagic colitis (hc) or the hemolytic uremic syndrome (hus), which is the main cause of acute renal failure in children. food...

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