Interleukin-6 (IL-6) activates cells by binding to the membrane-bound IL-6 receptor (IL-6R) and subsequent formation of a glycoprotein 130 homodimer. Cells that express glycoprotein 130, but not the IL-6R, can be activated by IL-6 and the soluble IL-6R which is generated by shedding from the cell surface or by alternative splicing. Here we show that cholesterol depletion of cells with methyl-be...

In this paper, a combinational optimization algorithm is introduced to obtain the best size and location of Static Compensator (STATCOM) in power systems. Its main contribution is considering contingency analysis where lines outages may lead to infeasible solutions especially at peak loads and it commonly can be vanished by load-shedding. The objective of the proposed algorithm is firstly to pr...

Activation of the P2X7 receptor by the extracellular damage-associated molecular pattern, adenosine 5'-triphosphate (ATP), induces the shedding of cell surface molecules including the low-affinity IgE receptor, CD23, from human leukocytes. A disintegrin and metalloprotease (ADAM) 10 mediates P2X7-induced shedding of CD23 from multiple myeloma RPMI 8226 B cells; however, whether this process occ...

During droughts, leaves are predicted to act as 'hydraulic fuses' by shedding when plants reach critically low water potential (Ψplant ), thereby slowing water loss, stabilizing Ψplant and protecting against cavitation-induced loss of stem hydraulic conductivity (Ks ). We tested these predictions among trees in seasonally dry tropical forests, where leaf shedding is common, yet variable, among ...

Foodborne salmonellosis costs the US $2.7 billion/year, including $100.0 million in annual losses to pork producers. Pigs colonized with Salmonella are usually asymptomatic with varied severity and duration of fecal shedding. Thus, understanding the responses that result in less shedding may provide a mechanism for control. Fifty-four pigs were inoculated with Salmonella enterica serovar Typhim...

In the present study, we apply proportional (P), proportional-integral (PI) and proportional-differential (PD) feedback controls to flow over a circular cylinder at Re=60 and 100 for suppression of vortex shedding in the wake. The transverse velocity at a centreline location in the wake is measured and used for the feedback control. The actuation (blowing/suction) is provided to the flow at the...

The voltage instability in power system increases with power demand and over stressing of existing transmission lines nearly to their limits. A serious type of voltage instability is voltage collapse. In this paper comparative study of two techniques, namely Voltage Collapse Prediction Index (VCPI) and Sensitivity analysis to find voltage collapse vulnerability of bus in a power system is done....

Highly pathogenic avian influenza H5N1 and Newcastle disease viral infections cause severe illness in chickens and vaccination is a strategic tool of controlling these diseases. Hence, this study was conducted to evaluate the efficacy of using both recombinant herpesvirus of turkey (rHVT-H5 and rHVT-F) vector vaccines at day-old, in the hatchery, under field conditions. Vaccinated chickens were...

The paper presents a Special Protection Scheme solution for the central Zagreb transmission system. The Central Zagreb transmission system is characterized by a highly meshed network with combined overhead and cable sections and a special operation of the 110 kV cable link between two power plants important for the city’s heat and electricity supply. The Special Protection Scheme is developed u...