Methods Venous blood samples were collected from 64 children in Pediatric Hospital Professor Heriberto Ferreira Bezerra (HOSPED) Federal University of Rio Grande do Norte (UFRN), Brazil. The laboratory investigation included measurement of serum IgG, IgM and IgA levels by imunoturbidimetry and the B lymphocyte quantification by flow cytometry with monoclonal antiCD19 for the cases that presente...

To determine the effect of anti-immunoglobulin antibodies on the measurement of the humoral immune response in hepatitis C virus (HCV) infected patients. Anti-immunoglobulin antibodies were defined using sheep immunoglobulins as a target to characterize distinct changes in patterns of immunoglobulin levels. Serum immunoglobulin A, G and M concentrations were measured by ELISA in 45 patients wit...

Viruses are a common cause of eye infection. The local mucosal response, with production of antibodies released into tears, is believed to provide an important immune defense against these agents. However very little information exists on the viral specificity of normal tear immunoglobulins. In this study we obtained tears, parotid saliva and serum from 40 normal subjects without eye disease. S...

PURPOSE To determine the effect of a fresh corneal wound or a healed corneal scar on the immunodiffusion of immunoglobulins into the cornea. METHODS F344 rats were immunized with human serum albumin (HSA) 1 week before an autologous rotational keratoplasty of the right cornea or 1 year after an autograft was performed. One group of rats also was treated with gentamicin-dexamethasone ointment ...

The effects of D-penicillamine on T-lymphocytes (rosette forming cells) and B-lymphocytes (surface IgG- and surface IgM-bearing cells) in peripheral blood of 13 patients with classical or definite rheumatoid arthritis were investigated at 4 weeks, 12 weeks and 24 weeks of treatment. At the same time, the determination of the concentrations of serum immunoglobulins and RA tests were carried out,...

igd myeloma is very rate. it differs from multiple myeloma of other classes in several aspects and its laboratory diagnosis may be difficult, as total plasma protein concentration is often normal, and a paraprotein peak may not be easily demonstrable by the conventional electrophoretic techniques. we report here two cases of igd myeloma investigated in this laboratory. immunochemical, biochemic...

background: determination of reference ranges of each serum protein in normal population of each country is required for studies and clinical interpretation. the aim of this study was defining reference range values of immunoglobulins and complement components in iranian healthy children. methods: this study was conducted from june 2003 to june 2006 in immunology, asthma and allergy research in...

Background: Major Depression Disorder (MDD) is a common disorder with preva-lence of 15% among men and up to 25% among women. In recent years the association of immune system alterations and MDD has been investigated. Assessments of immu-nologic and inflammatory responses in these patients enhance our knowledge of the eti-ology and pathogenesis of this disease. Objective: To investigate the cha...