Objective(s) Oxidative stress plays an important role in diabetic nephropathy pathogenesis. Rosmarinic acid, a plant phenolic compound, was first used as an antioxidant agent for inhibition of diabetic nephropathy. Material and Methods Forty male rats were uninephrectomized from the left flank.The rats were divided in four groups randomly; group one as control, group two diabetic untreatment...

The aim of the study was to investigate the extent and time course of aminoglycoside (AG)-induced serum creatinine elevation in patients with and without type 2 diabetes mellitus (DM2). This prospective study included patients with and without DM2 who were administered AG parenterally. The outcome of interest was the extent and time course of serum creatinine elevation suggestive of renal injur...

BACKGROUND Serum creatinine is the most widely used marker for estimating glomerular filtration rate (GFR). The aim of this study was to determine pediatric reference values for serum creatinine levels and eGFR values using data from a population-based study in Iran. METHODS Serum creatinine of 1594 subjects, aged 3 - 18 years, participating in phase 4 of the Tehran Lipid and Glucose Study (2...