The influence of oxidized frying oil (OFO) on the guinea pig hepatic microsomal xenobiotic-metabolizing enzyme system in the presence of different amounts dietary vitamin C was investigated. Weanling male guinea pigs were divided into four groups and were fed 15% oxidized frying oil diets supplemented with vitamin C at 300, 600, or 1,500 mg/kg (experimental diets) or a control diet that contain...

Mild-to-moderate vitamin C depletion in weanling guinea-pigs affects pyridinoline:deoxypyridinoline (collagen cross-link) ratios in femur shaft and urine, attributed to impairment of hydroxylation of collagen lysine. We investigated: (1). whether the picture at two time points is compatible with progressive accumulation of abnormal collagen; (2). whether any changes are seen in skin, where litt...

In order to study the interaction of glutathione, vitamin C and vitamin E under hyperoxia (95 % oxygen) and hyperbaric oxygen (2.5 atmospheric pressure), 20 days old male Guinea pigs were fed with basal vitamin C free diet, while receiving a vitamin C supplement of either high concentration (50 mg/day) or low concentration (1 mg/day) for two weeks. Animals were than exposed to hyperoxia and hyp...

Carotenoids, which impart yellow, orange, and/or red colors to many fruits, have antioxidant health properties. A series of experiments were undertaken to establish horticultural relationships to carotenoids in watermelon and mango in cooperation with U.S. commodity boards. Watermelon was assayed to determine effects of germplasm, storage temperature, and fresh cut on lycopene and beta carotene...

Background: Paraquat is nonselective bipyridyl herbicide that induces hepatotoxicity through oxidative stress. Vitamin C and chitosan have antioxidant as well as radical scavenger properties and show protective effects against reactive oxygen species (ROS). In the present study, hepatoprotective effects of chitosan and vitamin C were evaluated in common carp exposed to paraquat. Methods: Whi...

Antioxidants are substances which, when present in low concentrations, compared with that of an oxidisable substrate, significantly delay or prevent oxidation of the substrate (Halliwell & Gutteridge 1989). The most abundant antioxidants in fruits and vegetables are polyphenols and vitamins, especially vitamin C. Vitamins A, B and E and carotenoids are present to lesser extent in some fruits. T...

7 ABSTRACT: The antioxidant properties of methanolic extracts of six locally consumed plants in Nigeria were comparatively evaluated both in vitro and in vivo. The plants included V. amygdalina (bitter leaf); C. rubens (‘ebolo’); A. hybridus (‘tete’); J. tanjorensis (jatropha); G. africana (‘okazi’) and T. triangulare (water leaf). The in vitro study indicate that the DPPH radical scavenging ac...

Perianth development is specifically disrupted in mutants of the PETAL LOSS (PTL) gene, particularly petal initiation and orientation. We have cloned PTL and show that it encodes a plant-specific trihelix transcription factor, one of a family previously known only as regulators of light-controlled genes. PTL transcripts were detected in the early-developing flower, in four zones between the ini...

The total phenolic content, total flavonoid content, vitamin C content, and antioxidant activities of ethanol extracts from different kiwifruit varieties (Actinidia kolomikta, Actinidia arguta, Actinidia chinensis) were determined in this study. Multiple scavenging activity assays including the hydroxyl radical, O(2) (-)·radical, DPPH, and the ABTS(+) radical scavenging activity assays were use...