نتایج جستجو برای: sensory experience

تعداد نتایج: 477246  

Journal: :Neuron 2011
Michael C. Ashby John T.R. Isaac

Local recurrent excitatory circuits are ubiquitous in neocortex, yet little is known about their development or architecture. Here we introduce a quantitative technique for efficient single-cell resolution circuit mapping using 2-photon (2P) glutamate uncaging and analyze experience-dependent neonatal development of the layer 4 barrel cortex local excitatory circuit. We show that sensory experi...

Journal: :Acta medica Okayama 2012
Makiko Watanabe Hiroshi Ueno Shunsuke Suemitsu Eriko Yokobayashi Yosuke Matsumoto Shinichi Usui Hiroko Sujiura Motoi Okamoto

Recent studies have demonstrated the important role of immune molecules in the development of neuronal circuitry and synaptic plasticity. We have detected the presence of FcγRllB protein in parvalbumin-containing inhibitory interneurons (PV neurons). In the present study, we examined the appearance of PV neurons in the barrel cortex and the effect of sensory deprivation in FcγRllB-deficient mic...

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