Pure seminoma is a rare pathology of the young adult, often discovered in the early stages. Its prognosis is generally excellent and many therapeutic options are available, especially in stage I tumors. High cure rates can be achieved in several ways: standard treatment with radiotherapy is challenged by surveillance and chemotherapy. Toxicity issues and the patients' preferences should be cons...

We present a case of a 28-year-old male who presented with acute abdomen and was later diagnosed to be having ruptured intra-abdominal seminoma with hemoperitoneum, where the pre-operative diagnosis was not made. Laprotomy and complete excision were carried out. Rupture of intra-abdominal testicular seminoma is a rare cause of acute abdomen and hemoperitoneum. The pre-operative diagnosis is oft...

The results of treatment by infradiaphragmatic lymph node irradiation and orchiectomy in 232 patients with Stage I testicular seminoma seen between 1963 and 1983 are reported. Of this group, only five (2%) patients relapsed and none died from seminoma. Contralateral testicular tumours occurred in 12 patients and five developed second non-testicular malignancies. The acute and late morbidity of ...

Submit Manuscript | http://medcraveonline.com spermatic artery, hypercoagulability disorders and sickle cell disease [1-4]. Usually occurs between the third and fourth decade of life, the most common symptom is acute onset orchialgia; Scrotal US remains the first assessment tool, it is described as a wedge-shaped or rounded area of hypoechogenicity within the testis, at doppler evaluation with ...

Aim: A testicular germ cell tumour is not observed widely, but its incidence and mortality rates have increased in recent years. One of the most common forms this seminoma. Germ neoplasia situ (GCNIS) precursor The apelin/APJ axis many cancers a pathway that plays an active role angiogenesis, lymphangiogenesis, growth, migration. This study investigated cellular distributions apelin APJ protein...

We report the case of a 33-year-old male with primary seminoma of the anterior mediastinum with initial clinical manifestations suggestive of heart disease.

BACKGROUND Patients with a primary pure seminoma in the testis who have elevated serum alpha-fetoprotein are rare and should be treated as patients with nonseminomatous germ cell tumors. However, nonpalpable testicular tumors in this condition have never been reported. We describe a case of nonpalpable pure testicular seminoma with elevated serum alpha-fetoprotein presenting retroperitoneal met...

OBJECTIVE The aim of this report is to address treatment outcomes of patients with early-stage seminoma in a developing country with special reference to patients with history of surgical violation of the scrotum and the potential predictors of disease relapse. PATIENTS AND METHODS Seventy four patients with pure seminoma were treated at King Hussein Cancer Center (Amman, Jordan) between 2003...