PURPOSE Preliminary data suggest that hK11 is a novel serum biomarker for prostate and ovarian cancer. To examine the enzymatic characteristics of hK11, we purified and functionally characterized native hK11 from seminal plasma. EXPERIMENTAL DESIGN hK11 was purified from seminal plasma by immunoaffinity chromatography and characterized by kinetic analysis, electrophoresis, Western blots, and ...

Background: Vajikarana herbs from Ayurveda are known to enhance the sexual performance in folklore. The objective is to evaluate their effect by molecular and pharmacological screening. Materials and Methods: In the present study, the effect of four Vajikaran Rasayana herbs on penile erection, sperm count, seminal fructose content in vivo and nitric oxide (NO) release in vitro was assessed. Pen...

Variations in the ejaculatory abstinence durations suggested by different guidance bodies have resulted in a growing concern among researchers over what the concise period of ejaculatory abstinence for an optimal semen sample ought to be. Several studies have been undertaken to examine the association between the length of sexual abstinence and semen characteristics. Not all studies, however, h...

background: glycosidases profusion in male reproductive fluids suggests a possible relationship with sperm function. although hexosaminidase (hex) is the most active glycosidase in epididymal fluid and seminal plasma, as well as in spermatozoa, glucosidase is considered a marker for epididymal function and azoospermia. objective: the aim of this study was to determine hex activity in seminal pl...

OBJECTIVE Growth hormone and its mediator, insulin-like growth factor-1 (IGF-1), have been suggested to exert gonadotropic actions in both humans and animals. The present study was conducted to assess the relationship between serum IGF-1 concentration, seminal plasma concentration, and sperm parameter abnormalities. METHODS A total of 79 men were enrolled in this study from December 2011 to J...

Sixteen adult New-Zealand White rabbit males at the age of 6 months and weight of 2.5 ± 0.14 kg were used to study semen characteristics and some biochemical and enzymatic properties of seminal plasma, and blood plasma testosterone during spring and summer seasons. The averages of maximum and minimum ambient temperature in both seasons were 27.1 oC and 18.9 oC in spring, versus 32.2 oC and 26.5...

Background: The lipid peroxides and their degradation products are highly toxic to spermatozoa and may play a major role in sperm dysfunction. The purpose of this study was to determine the level of lipid peroxidation as indicated by malondialdehyde (MDA) in the spermatozoa and seminal plasma of asthenozoospermic and normozoospermic males. In addition, correlation of lipid peroxidation with mot...