Cellular behavior is orchestrated by the complex interactions of a myriad of intracellular signal transduction pathways. To understand and investigate the role of individual components in such signaling networks, the availability of specific inhibitors is of paramount importance. We report the generation and validation of a novel variant of an RNA aptamer that selectively inhibits the mitogen-a...

The main objective of this research is theoretical and experimental investigation of the surfaces modification of SU8, PDMS, SiO2 and Si by RF plasma treatment. Physical-chemical reactions at room temperature can be used for the modifications of the surfaces in plasma, by modifying the contact angle, superficial polymerization, or by creating hydrophilic and/or hydrophobic regions on the surfac...

Foege, W. H., J. D. Millar and J. M. Lane (CDC, Atlanta, Ga. 30333). Selective epidemiologic control in smallpox eradication. Amer J Epidem 94: 311-315, 1971.—A change of strategy was instituted in the West and Central Africa Smallpox Eradication Program in the fall of 1968. High priority was given to eliminating smallpox foci rather than limiting activities to mass vaccination. The progress of...

First lab-on-chip devices based on active transport by biomolecular motors have been demonstrated for basic detection and sorting applications. However, to fully employ the advantages of such hybrid nanotechnology, versatile spatial and temporal control mechanisms are required. Using a thermo-responsive polymer, we demonstrate the selective starting and stopping of modified microtubules gliding...

The response to uniform selection may occur in alternate ways that result in similar performance. We tested for multiple adaptive solutions during artificial selection for high voluntary wheel running in laboratory mice. At generation 43, the four replicate high runner (HR) lines averaged 2.85-fold more revolutions per day as compared with four non-selected control (C) lines, and females ran 1....

This paper introduces an off-tag RFID access control mechanism called “Selective RFID Jamming”. Selective RFID Jamming protects low-cost RFID tags by enforcing access control on their behalf, in a similar manner to the RFID Blocker Tag. However, Selective RFID Jamming is novel because it uses an active mobile device to enforce centralized ACL-based access control policies. Selective RFID Jammin...

In this paper, we would like to study the analytical model of Transmission Control Protocol – Selective Acknowledgement (TCP SACK) by deriving its fast recovery probability in wireless links. Recently, there exist several variants of TCP, for instances Tahoe, Reno, New Reno, Vegas, Westwood and SACK. TCP Reno is the most popular TCP implementation in the Internet today. Reno’s fast recovery alg...

We propose an efficient flow and error control scheme for highthroughput transport protocols by using a second-order rate control, called the -control, and a new sliding-window scheme for error control. The -control minimizes the packet retransmissions by adjusting the rate-gain parameter to the variations in the number and round-trip times (RTTs) of cross-traffic flows that share the bottlenec...

objectives to explore the effect of a selective 10-week corrective exercise with an emphasis on gait training activities (gta) on the number of falls (nofs), fear of falling, functional balance, timed up and go (tug) test among pd patients. background posture instability and unsteady gait disorders in parkinson’s disease (pd) usually contribute to fall-related fractures. fall-related trauma in ...