INTRODUCTION A Phosphate Centric Forum, supported by Genzyme Corporation, was held on 24–25 June, 2010 at the Sheraton West Park Hotel, Munich, Germany, in which 25 medical and scientifi c experts in the fi eld of chronic kidney disease-related mineral and bone disorder (CKD-MBD) met to present and discuss the central role of phosphate in the development of CKD-MBD, on which research has now ce...

Lifetime physical inactivity interacts with secondary aging (i.e., aging caused by diseases and environmental factors) in three patterns of response. First, lifetime physical inactivity confers no apparent effects on a given set of physiological functions. Second, lifetime physical inactivity accelerates secondary aging (e.g., speeding the reduction in bone mineral density, maximal oxygen consu...

Disorders of the parathyroid glands most commonly present with abnormalities of serum calcium. Patients with primary hyperparathyroidism, the most common cause of hypercalcemia in outpatients, are often asymptomatic or may have bone disease, nephrolithiasis, or neuromuscular symptoms. Patients with chronic kidney disease may develop secondary hyperparathyroidism with resultant chronic kidney di...

[1] Nitrous acid is an important precursor for OH radicals in the polluted troposphere. The heterogeneous conversion of NO2 to HONO, however, is currently not well understood. Measurements of HONO and NO2 in Phoenix in summer 2001 using long path DOAS show ratios of chemically formed secondary [HONO] to [NO2] that rarely exceeded 3%. During two nocturnal dust storm events, however, a significan...

OBJECTIVE To evaluate lumbar bone mineral density (BMD) in girls with eating disorders in the beginning of the treatment, at six months, and after one year of treatment. SUBJECTS AND METHODS This prospective study involved 35 female adolescents with AN or EDNOS treated during one year. Lumbar (L1-L4) bone mineral density by DXA was performed in the beginning of treatment, at six months, and a...

We have analyzed a frondelite mineral sample from the Cigana mine, located in the municipality of Conselheiro Pena, a well-known pegmatite in Brazil. In the Cigana pegmatite, secondary phosphates, namely eosphorite, fairfieldite, fluorapatite, frondelite, gormanite, hureaulite, lithiophilite, reddingite and vivianite are common minerals in miarolitic cavities and in massive blocks after triphyl...

BACKGROUND AND PURPOSE The adverse effects of newer antiepileptic drugs are not well-known. This study assessed the impact of oxcarbazepine (OXC) treatment on bone turnover. METHODS Forty-four children with idiopathic focal (and/or secondarily generalized) epilepsy who had been treated with OXC for more than 1 year were compared with 33 healthy, age- and sex-matched children. Serum calcium, p...

Patients with chronic kidney disease (CKD) are affected by mineral and bone disorder (MBD), resulting in abnormalities in serum calcium (Ca), phosphorous (P) and parathyroid hormone (PTH). Changes in mineral metabolism have also been associated with higher rates of both all-cause and cardiovascular-related mortality. The majority of haemodialysis patients are also deficient in the endogenous ho...

This study investigated the ability of One-Up Bond alone and mineral trioxide aggregate (MTA), with and without a secondary seal of One-Up Bond or SuperEBA to seal saucer-shaped perforation defects in human molars. Cusps were removed, roots were amputated, and endodontic therapy completed on 40 extracted teeth. A cylindrical hole was made in each tooth from the furcation area to the chamber, in...

Within the realm of modern science, many of the most challenging fields of endeavor involve interfuces. Not only are interfaces highly complex environments in and of themselves, they also require interdisciplinary research in a time of increased specialization. Soils are the quintessential interfaces at the earth’s surface, for they are the links connecting the atmosphere, the hydrosphere, the ...