PURPOSE To determine the incidence and contribution of different types of glaucoma to blindness at Irrua Specialist Teaching Hospital, a suburban tertiary care hospital in Edo State, Nigeria. METHODS Medical records of all new patients with glaucoma who presented to the eye clinic of the hospital from June 2007 to May 2009 were reviewed. RESULTS Out of a total of 2,742 new patients seen ove...

KORESPONDENCIJA / CORRESPONDENCE Authors report the case of a 59-year old woman with bilateral posterior lens luxation in vitreous, medically controlled glaucoma and corneal adherent leucoma with vascularization in whom Marfan syndrome was diagnosed. e patient underwent complete clinical eye and systemic examinations and blood samples were drawn for mutational screening of €brillin1 gene (FBN1...

Iris neovascularization (NVI) in eyes with newly diagnosed retinoblastoma is a hallmark of advanced tumor. These eyes often display secondary glaucoma and additional partial or complete retinal detachment. From a clinical perspective, NVI with secondary glaucoma is noted in approximately 12% of eyes with retinoblastoma, and from a pathology perspective, NVI has been found in 44% of eyes followi...

Accumulative evidence has indicated that apoptosis is the common pathway for retinal ganglion cell (RGC) death and that autophagy promotes survival of RGCs in glaucoma. In the present review, it was hypothesized that the progressive death of RGCs in glaucoma involves another novel non‑apoptotic programmed cell death, known as 'paraptosis', in the early stages of glaucoma. Paraptosis may be acco...

Glaucoma is the most common age-related optic nerve disease and also the most common neuropathy, affecting approximately 60 million people worldwide in its most common forms. This figure is expected to rise to 80 million by 2020. Glaucoma is a neurodegenerative disease in which various triggers induce cascades of secondary events, which ultimately lead to apoptotic retinal ganglion cell (RGC) d...

INTRODUCTION This case report presents the pressure-lowering effect of transluminal fistula occlusion in a patient suffering from secondary glaucoma due to carotid cavernous fistula (CCF). CASE REPORT A 76-year-old Caucasian woman presented with dilated epibulbar vessels with elevated intraocular pressure (IOP, >30 mmHg) as well as glaucomatous excavations of the optic disc in both eyes. Cere...

AIM To report long term efficacy and complications of retinectomy as an intraocular pressure lowering procedure for intractable glaucoma. METHODS This was a consecutive interventional case series. In 44 consecutive eyes (39 patients, 22 men and 17 women) retinectomy was performed to lower the intraocular pressure (IOP) in patients with uncontrolled IOP (>35 mm Hg for more than 4 months) despi...

Eisenmenger syndrome refers to reversal of shunt and central cyanosis due to pulmonary hypertension induced by congenital heart disease with a large systemic-to-pulmonary shunt. We report a case of a 17-year-old man with Eisenmenger syndrome who presented with gradual deterioration in visual acuity and was diagnosed with advanced secondary open angle glaucoma. There have been reports of patient...

The aim of this study was to examine the secondary visual cortex functional disorder in patients with glaucoma and large pituitary adenoma by functional magnetic resonance imaging, and to determine the correlation between visual field defect and primary visual cortex activation. Results showed that single eye stimulation resulted in bilateral visual cortex activation in patients with glaucoma o...

PURPOSE To investigate the usefulness of visual field testing in the diagnosis and subsequent management of glaucoma in a specialist glaucoma clinic at Groote Schuur Hospital, Cape Town, South Africa. METHODS A retrospective case note review of 344 patients who attended the glaucoma clinic between January and June 2010. RESULTS The study population consisted of 201 (58%) females and 143 (42...