This review addresses the role of nitrogen (N) in vine balance and grape composition. It offers an integrative approach to managing grapevine N nutrition. Keeping mind that excess is just as detrimental wine quality depletion, control status, ultimately must composition, critical for high-quality production. fertilisation has been intensively used past century, despite plants absorbing only 30 ...

Algae extract biostimulants increase nutrient uptake, stress tolerance, and productivity in several crops. However, there is still a gap the knowledge of mechanisms action algae extracts on nitrogen plant metabolism. This study aimed to evaluate effect commercial Ascophyllum nodosum metabolism nodulating soybean plants their productivity. Two concentrations (0.25% 0.50%) were used, which applie...

The effects of plant polyphenols on carbohydrate and/or lipid metabolism disorders have wide experimental and clinical justification; however, their are limited due to low bioavailability. Thus, the development technological approaches enhancing effectiveness stability is relevant.The aim this work was evaluatein vivothe from bilberry leaves fruits, sorbed brown buckwheat flour, C57Bl/6c mice w...

Abstract PII superfamily consists of signal transduction proteins found in all domains life. PII-like evolved to fulfill diverse, yet poorly understood cellular functions. We recently identified the protein SbtB cyanobacteria as a sensor various adenine nucleotides including second messengers cAMP and c-di-AMP. This highlights central switch-point cyanobacterial physiology, integrating not only...

The metabolism of exogenous [3H]diacylglycerols by intact human platelets was studied in order to examine: 1) the metabolic fate of these second messengers in an intact cell, 2) the effect of diacylglycerol kinase and diacylglycerol lipase inhibitors on this metabolism, 3) the effect of agonist stimulation on metabolism, and 4) the dependence of metabolism on diacylglycerol chain length. When 2...

Introduction . Chronic pain syndrome in the development of malignant neoplasms has a complex polyethological character. The study pathogenetic mechanisms during growth transplanted tumor experiment can open up broad perspectives for creation new domestic analgesic drugs use oncology. Aim : To serotonin inactivation coefficient (SIC), ratio (S) and its main metabolite 5-hydroxyindolacetic acid (...

Microbial fuel cells (MFCs) were used to monitor metabolism changes in Clostridium acetobutylicum fermentations. When MFCs were inoculated with C. acetobutylicum, they generated a unique voltage output pattern where two distinct voltage peaks occurred over a weeklong period. This result was markedly different to previously studied organisms which usually generate one sustained voltage peak. Ana...

Prostate cancer is the second leading cause of cancer-related deaths among men worldwide. Early diagnosis increases survival rates in patients but the survival rate has remained relatively poor over the past years. Increasing evidence shows that altered metabolism is a critical hallmark in prostate cancer. There is a strong need to explore the molecular mechanisms underlying cancer metabolism f...

Enhanced proliferation and survival are common features of cancer cells. Cancer cells are metabolically reprogrammed which aids in their survival in nutrient-poor environments. Indeed, changes in metabolism of glucose and glutamine are essential for tumor progression. Thus, metabolic reprogramming is now well accepted as a hallmark of cancer. Recent findings suggest that reprogramming of lipid ...