Models of anxiety and fear of novelty were evaluated using correlations and principal component analysis. A total of 84 pigs (LandracexYorkshire) from nine different litters were subjected to a tonic immobility (TI) test at the age of 2.5 weeks, an elevated plus-maze (EPM) at the age of 6 weeks, a light/dark (L/D) exploration test at the age of 7 weeks and an open-field (OF) test at the age of ...

We introduce and analyze an exterior-pointmethod (EPM) for constrained optimization problems with both inequality constraints and equations. We show that under the standard second-order optimality conditions the EPM converges to the primal–dual solution with 1.5-Q-superlinear rate.

A spinning disc reactor was investigated as a process intensification technology for photocatalysis and compared with a conventional annular reactor. It was found that the average photonic efficiency achieved in the SDR was three times larger than the maximum photonic efficiency achieved in the annular reactor, 0.19±0.08% versus 0.062 ± 0.009%, indicating that the SDR is significantly more effi...

We introduce and analyze an exterior-point method (epm) for constrained optimization problems with both inequality constraints and equations. We show that under the standard second-order optimality conditions the epm converges to the primal-dual solution with 1.5-Q-superlinear rate.

BACKGROUND Spasticity is a motor disorder that interferes with mobility and affects the quality of life. Different approaches have been utilized to address patients with spastic diplegia, among which is selective dorsal rhizotomy (SDR). Although SDR has been shown to be efficacious in treating spastic patients, many neurologists and neurosurgeons are not well aware of the procedure, its indicat...

1Department of Statistics, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark 2Department of Gynecology and Obstetrics, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, Denmark 3Department of Biochemistry & Molecular Biology, Proteom Research Group, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark 4 Department of Biochemistry, Pharmacology & Ge...

Background: Medicinal plants with natural antioxidants have been shown to be beneficial in a variety of complications such as anxiety. The elevated plus-maze (EPM) is one of the most widely used models to assess anxiety in small rodents. Objectives: This study was designed to characterize the anxiolytic-like activity of Borago officinalis (Linnaeus, family Boraginaceae) or Borage flowers extrac...

The elevated plus-maze (EPM) is currently used to study the neural basis of anxiety as well as to assess the anxietymodulating activity of various pharmacological agents. Although the anxiogenic stimulus is supposed to be the open space in this test, the anxiety-related behavioral baseline of rats is sensitive to numerous methodological-linked parameters [1]. In order to improve the quality of ...

The antiproliferative activity of the aspirin derivative [2-acetoxy-(2-propynyl)benzoate]hexacarbonyldicobalt (Co-ASS) and its analogue hexacarbonyl[μ-(2-ethylphenyl)methanol]dicobalt (Co-EPM) was investigated on malignant pleural mesothelioma (MPM) cell lines, having an epithelioid or a sarcomatoid phenotype. In sarcomatoid cell lines Co-ASS was more potent than Co-EPM and the prototypal metal...

Rat bone marrow (BM) small cells were enriched by velocity sedimentation, further separated by means of free-flow electrophoresis, and characterized using Tand B-cell-specific surface markers. More than 80% of these cells were small lymphocytes by morphological criteria and reacted with lymphocyte-specific antisera. A minority of cells had high electrophoretic mobility (EPM), carried surface an...