Twenty-three children were admitted to a pediatric intensive care unit for scorpion envenomation with severe hypertension. The hypertension responded to analgesics and sedatives in 15 (65 percent) of the 23. The remaining eight children required specific antihypertensive therapy, and their condition promptly responded to intravenous hydralazine and sublingual nifedipine; rebound hypertension wa...

background: to explore the oral absorption of scorpion venom an elisa were designed in this study. scorpions and their venom were been used for centuries as medical treatments in traditional medicine. the oral administration of drug referred as the convenient way, as there was not any publication about gastro-intestinal absorption of scorpion venom; this experiment checked oral absorption of me...

BACKGROUND Scorpion antivenom (SAV) is specific antidote to scorpion venom..SAV did not prevent the cardiovascular morbidity and mortality (autonomic storm), hence its utility in the management for severe scorpion envenomingmay be limited. Since 1983 the advent of prazosin revolutionized the management of severe scorpion sting. Since 2002 SAV against Indian red scorpion (IRS) for the treatment ...

In this study, Mesobuthus gibbosus and Mesobuthus eupeus eupeus venom samples were compared for lethality, in vivo effects and proteins. Neutralization capacity of monovalent Androctonus crassicauda antivenom (RSHA anti-Ac) was tested against the lethal effects of the venoms.Venom was obtained from mature scorpions by electrical stimulation of the telson. The lethality of the venom and potency ...

in tropical and subtropical countries, envenomation by scorpions (so-called scorpionism) represents a serious public health problem. in the present study, the toxic effects of mice ld50 injections of mesobuthus eupeus (me) venom on the kidney and liver of anesthetized rabbits were investigated. six rabbits were selected and alt, ast, bun and creatinine were measured at 0, 1 and 3 hours after...

INTRODUCTION This study investigated scorpionism profile in the State of Amazonas, Brazil. METHODS Data referring to stinging incidents were obtained from the National Databank of Major Causes of Morbidity. Information on the scorpion species involved was obtained from the Amazonas State health units. RESULTS Amazonas has a scorpionism rate of 8.14 cases/100,000 inhabitants. Some municipali...

Scorpion stings and snake bites are major health hazards that lead to suffering of victims and high mortality. Thousands of injuries associated with such stings and bites of venomous animals occur every year worldwide. In North Africa, more than 100,000 scorpion stings and snake bites are reported annually. An appropriate determination of the 50% lethal doses (LD₅₀) of scorpion and snake venoms...

background : antivenom is still widely used in the treatment of envenomation as there are no vaccines or other effective agents available against animal venoms. recently, neurotoxins named birtoxin family have been described from parabuthus transvaalicus and androctonus crassicauda. the aim of the present study was to test the antibirtoxin antibodies for their ability to neutralize the lethal e...