Janus kinase 3 (JAK3) is a non-receptor tyrosine kinases family of protein which is comprised of JAK1, JAK2, JAK3 and TYK2. It plays an important role in immune function and lymphoid development and it only resides in the hematopoietic system. Therefore, selective targeting JAK3 is a rational approach in developing new therapeutic molecule. In this study, about 116 JAK3 inhibitors were collecte...

in this paper, the variational iteration method proposed by ji-huan he is applied to solve both linear and nonlinear schrodinger equations. the main property of the method is in its flexibility and ability to solve linear and nonlinear equations accurately and conveniently. in this method, general lagrange multipliers are introduced to construct correction functionals to the problems. the multi...

This paper deals with the Legendre wavelet (LW) collocation method for the numerical solution of the radial Schrodinger equation for hydrogen atom. Energy eigenvalues for the hydrogen bound system is derived -13.6 eV. Numerical results of the ground state modes of wave function for the hydrogen R(r) or the electron probability density function, has been presented. The numerical results ha...

The linearization of the classical Boussinesq system is solved explicitly in case nonzero boundary conditions on half-line. analysis relies unified transform method Fokas and performed two different frameworks: (i) by exploiting recently introduced extension Fokas's to systems equations (ii) expressing linearized as a single, higher order equation, which then via usual version transform. result...

In chis letter we integrate numerically the time dependent Schrodinger equation to investigate the use of a semi-infinite laser pulse to localize an electron in one of the wells of a double well quantum structure. Under certain conditions the system can be driven to emit stroxigly low frequency radiation.

The classical Weyl formula expresses the leading term of the asymptotics of the counting function N(lambda, H) of the spectrum of a self-adjoint operator H in an invariant form: one can "hear" the volume of the subset of the cotangent bundle where the symbol of the operator H is less than lambda. In particular, it is applicable to Schrodinger operators with electric potentials growing at infini...