The frequency of sister chromatid exchange (SCE) has been followed sequentially after the addition of SV40 to human diploid fibroblast cultures. The SCE frequency was nearly the same in uninfected controls and in infected cultures before they became tumor antigen positive. When cells exhibited tumor antigen, the SCE frequency increased over a wide range, and changes in chromosome number and str...

Homologous recombination involving sister chromatids is the most accurate, and thus most frequently used, form of recombination-mediated DNA repair. Despite its importance, sister chromatid recombination is not easily studied because it does not result in a change in DNA sequence, making recombination between sister chromatids difficult to detect. We have previously developed a novel DNA templa...

The job shop problem is an important part of scheduling in the manufacturing industry. A new intelligent algorithm named Shuffled Complex Evolution (SCE) algorithm is proposed in this paper with the aim of getting the minimized makespan. The sequence mapping mechanism is used to change the variables in the continuous domain to discrete variables in the combinational optimization problem; the se...

The aim of this study was to develop a fast test for local photoreceptor alignment. Photoreceptor alignment is an important indicator of retinal integrity. Digitized images of fundus reflectance were obtained for 20-30 pupil entry positions with a custom built scanning laser ophthalmoscope (SLO). The data permitted the calculation of curve peakedness of the optical Stiles-Crawford effect (SCE) ...

The objective of this paper is to demonstrate the practice of the SubGraph Isomorphism (SGI) algorithm on solving the problem of SubCircuit Extraction (SCE). The netlist representation of circuits is discussed first because it has caused the dilemma to the existing SCE approach. Then, based on mapping focus of Edge Unit (EU), an algorithmic solution is exhibited to fulfill the void of circuit c...

The frequency of sister chromatid exchange (SCE) was analyzed in bone marrow cells of 16 patients with chronic myeloid leukemia. We have compared the SCE frequency in these patients, in both chronic and blastic phases of the dis ease, to that of normal individuals. The frequency of SCE in blastic-phase chronic myeloid leukemia patients (mean, 1.86/ cell) was significantly lower than that in chr...

Many recent studies reveal that sea ice concentration (SIC) in the eastern Arctic and snow cover extent (SCE) over central Eurasia in late autumn are potential predictors of the winter North Atlantic Oscillation (NAO). We used maximum covariance analysis (MCA) to investigate the links between autumn SIC in the Barents-Kara Seas (BK) and SCE over Eurasia (EUR) with winter (DJF) sea level pressur...

The self-assembly of 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine (TPyP) on Au(111) electrodes was investigated. The adlayer structure was found to depend on the electrode potential. At positive potentials (>0.5V(SCE)), a disordered layer of TPyP is formed on the Au(111) electrode. STM images showed that the disordered molecules are immobile. At negative potentials (-0.2V(SCE)), however, the mo...

Aberrant transforming growth factor β1 (TGFβ1) signaling plays a pathogenic role in the development of vascular fibrosis. We have reported that Schisandra chinensis fruit extract (SCE), which has been used as a traditional oriental medicine, suppresses TGFβ1-mediated phenotypes in vascular smooth muscle cells (VSMCs). However, it is still largely unknown about the pharmacologic effects of SCE o...