A rat model of spinal cord injury was established using the weight drop method. A cavity formed 14 days following spinal cord injury, and compact scar tissue formed by 56 days. Enzyme-linked immunosorbent assay and polymerase chain reaction enzyme-linked immunosorbent assay results demonstrated that glial fibrillary acidic protein and telomerase expression increased gradually after injury, peak...

Radiofrequency ablation is a promising procedure for treating atrial fibrillation (AF) that relies on accurate lesion delivery in the left atrial (LA) wall for success. Late Gadolinium Enhancement MRI (LGE MRI) at three months post-ablation has proven effective for noninvasive assessment of the location and extent of scar formation, which are important factors for predicting patient outcome and...

Background: Hepatic fibrosis is a progressive disease caused by incessant irritation of the liver tissue, which results in the formation of scar tissue. Fibrotic progression and subsequent scar tissue formation is correlated to changing liver mechanical properties. This correlation may be used to assess the state of the disease, and hence methods to determine the elastic modulus of the liver ar...

Spinal cord injury is followed by glial scar formation, which has positive and negative effects on recovery from the lesion. More than half of the astrocytes in the glial scar are generated by ependymal cells, the neural stem cells in the spinal cord. We recently demonstrated that the neural stem cell-derived scar component has several beneficial functions, including restricting tissue damage a...

• Traumatic lesions to the spinal cord of adult individuals will cause degeneration of the severed distal axons, retraction of the severed proximal axons, scar formation in the damaged area, and eventually regenerative signs, which will occur along the retracted proximal axons. Growth cone-like appendages appear and regenerating axons enter the scar tissue. Within the relatively unstructured sc...

BACKGROUND We conducted an experimental study to compare the effect of massage using topical agents (Kelo-cote or Contractubex) on scar formation by massaging the healed burn wound on the dorsal area of Sprague-Dawley (SD) rats. METHODS Four areas of second degree contact burn were made on the dorsal area of each of 15 SD rats, using a soldering iron 15 mm in diameter. After gross epitheliali...

BACKGROUND The acute coronary syndrome diagnosis includes different classifications of myocardial infarction, which have been shown to differ in their pathology, as well as their early and late prognosis. These differences may relate to the underlying extent of infarction and/or residual myocardial ischemia. The study aim was to compare scar and ischemia mass between acute non-ST elevation myoc...