Ewing's sarcoma, peripheral primitive neuroectodermal tumor, and Askin's tumor comprise a single family of tumors, the Ewing's family of tumors, which is characterized by chromosomal translocation. Ewing's sarcoma is known as a malignancy of childhood, but with a median age of 15 years at diagnosis, it should equally be regarded as a malignancy of adolescence and young adulthood. There is much ...

The Ewing sarcoma family of tumors comprises a rare class of cancers of mesenchymal origin. Cases of Ewing's sarcoma in the central nervous system - specifically, intracranial Ewing's - are extremely rare. Almost all reported cases have occurred in children. However, this rare presentation can also occur in the adult population. It is important to distinguish these tumors from primitive neuroec...

Guaroa virus inhibited or destroyed ascites tumors (Ehrlich or Sarcoma 180) of Swiss white mice when inoculated intraperitoneally from 1 to 6 days after tumor in jection. Thirty of 79 virus-treated mice survived 30 days after injection of Ehrlich ascites cells without accumulation of ascites, whereas all but two of 73 controls died with a mean survival time of 15 days. With Sarcoma 180 ascites,...

Among 1,000 selected compounds and antibiotics tested against all or portions of the tmnor spectrum (33 tumors), cytoxan was the most effective, having a marked inhibitory to complete inhibitory effect on ~6 out of 38 tumors. Cytoxan (50 mg /kg /day for mice; ~5 m g / k g / d a y for rats) had a destructive effect on well established 7-day-old Sarcoma T5~41, Carcinoma 10~5, Lewis bladder carcin...

Langerhans cell neoplasms, which include histiocytosis and sarcoma, are tumors that originate from dendritic cells. sarcoma is defined as a high-grade neoplasm with overtly malignant cytological features the cell-like phenotype, generally has poorer prognosis more aggressive phenotype than histiocytosis. Insulin-like growth factor 2 messenger RNA-binding protein 3 (IGF2BP3 or IMP3) an oncofetal...

OBJECTIVE The present study was done to find out the frequency of malignant tumors of bone and to categorize the prevalence of various histological types of osseous malignancies with respect to age, sex and site of origin. SETTING This study included consecutive cases of malignant bone tumors, which were diagnosed in the department of pathology at the Aga Khan University Hospital, Karachi dur...

Synovial sarcoma (SS) is a soft tissue, generally deep seated neoplasms that occurs generally in the proximity of large joints. We report of a case of a 33-year-old man who was diagnosed with primary SS of the kidney which is an extremely rare tumor that accounts for less than 2% of malignant renal tumors. Contemporary management of renal synovial sarcoma includes surgical resection and ifosfam...

Myeloid sarcoma initially occurring in the sacral canal is often misdiagnosed as other pathological tumors on MRI due to the lack of a definite history or clinical evidence of granulocytic leukemia. Here, we report a case of 24-year-old male patient with myeloid sarcoma misdiagnosed radiologically. On MRI, sacral myeloid sarcoma is characterized by homogeneous signal intensity, marked enhanceme...

Skeletal muscle is remarkably free of neoplasms despite its great body mass. Metastatic tumors to skeletal muscle are distinctly uncommon. Primary myogenous tumors (defined as those whose cytoplasm contains myofibrils) are infrequent, compared to primary lesions of supporting stroma and vascular origin. Almost all non-myogenic tumors of striated muscle occur also in other areas of the body and ...

In tissue cultures of C-57 black mouse heart and sarcoma T-241, beta-2-thienyl-DL-alanine acts specifically as a phenylalanine antagonist. Heart cultures can transaminate between beta-2-thienyl-DL-alanine and phenylpyruvate to form L-phenylalanine and thus block the toxic action of the remaining beta-2-thienyl-DL-alanine, whereas sarcoma T-241 cultures cannot. Of eleven mouse tumors and four ra...