Vascular or lymphatic malformation can present as a diffuse tongue mass, suggested by a bluish hue or overlying vesicles. Tuberculosis, hypothyroidism, acromegaly, and idiopathic muscular hypertrophy manifest clinically as macroglossia, for which the diagnosis is aided by the medical history and other physical signs. Moreover, the nodular appearance of the macroglossia suggests other pathologie...

OBJECTIVE This study presents a clinicopathologic review of cases of submandibular salivary gland tumours at the Lagos University Teaching Hospital, Nigeria, over a period of 17 years. METHODS The records of all patients with histological diagnosis of submandibular salivary gland tumours at the Lagos University Teaching Hospital over a period of 17 years (January 1990 to December 2006) were r...

Introduction: High-dose radioactive iodine therapy in differentiated thyroid cancer (DTC) may adversely affect the salivary gland function. This study is aimed to evaluate the effect of radioactive iodine (RAI) with dose of 100 mCi in DTC patients compared to lower doses of less than 30 mCi in hyperthyroid cases. Methods: Fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...

Salivary gland cancers (SGCs) are rare, accounting for less than 5% of all malignancies the head and neck region, morphologically heterogeneous. The diagnosis is mainly based on histology, with complementary aid molecular profiling, which helpful in recognizing some poorly differentiated, borderline, or atypical lesions. Instrumental imaging defines diagnosis, representing a remarkable tool tre...

Previous studies have suggested that the dependence of low grade B cell gastric lymphoma on infection of the gastric mucosa with Helicobacter pylori results from help provided by H pylori specific tumour infiltrating T cells. ELISPOT analysis was used to characterise functional subpopulations of tumour infiltrating T cells. The production of the TH1 cytokine interferon gamma and TH2 cytokines i...

Increasing evidence suggests that in many cancer types only a minor proportion of cells, the so-called ‘cancer stem cells’, is responsible for fostering continuous tumour growth. Similar to the non-malignant stem cells that maintain tissue homeostasis, cancer stem cells are seemingly able to self-renew indefinitely. A recent study from the lab of Walter Birchmeier, in cooperation with Ulrike Zi...

background and aims. salivary gland tumors are rare and specific lesions. there are differences in the incidence and frequency of salivary tumors in both minor and major salivary glands in different countries. this study was carried out to determine the prevalence of major and minor salivary gland tumors in ahvaz in the south of iran. materials and methods. all the cases, recorded in imam khome...

The clinical, light microscopic, ultrastructural, immunocytochemical and cytogenetic features of a case of monocytoid B cell lymphoma were investigated. The tumour initially affected the cervical and supraclavicular nodes, but 33 months later affected the left parotid salivary gland. The patient had subclinical Sjögren's syndrome. The neoplastic cells showed characteristic morphological feature...

Salivary gland tumours (SGT) are rare, comprising about 5% of head and neck tumours with a higher incidence reported in the western compared with the African centres. There are few studies on SGTs that have been conducted in Africa. A descriptive retrospective study was done to describe the demographic characteristics, site distribution and histological patterns of SGT at a University teaching ...