P63 is basically a stem cell marker. It belongs to p53 protein family which comprises of transcription factors p53, p63, p73. P63 also possesses two isoforms which are interestingly with opposing characters. Its complexity remains unrevealed with helps in maintenance of genetic stability of germ cells, mechanisms of p63 behaves both monogenic as well as tumor suppressor of its various isoforms....

introduction: salivary gland tumors are relatively rare and constitute 3-4% of all head and neck neoplasms. the majority (70%) of salivary gland tumors arise in the parotid gland. recommended treatment for a parotid mass is surgical excision with a surrounding cuff of normal tissue to prevent recurrence. materials and methods: this is a retrospective study of 300 patients who were operated by a...

ACCs are usually low grade, well‐differentiated neoplasms that constitute 2.5%–4% of parotid gland tumors.[1] The mean age of occurrence is in the fifth decade, but the papillary cystic variant is reported to occur in younger patients compared to the classic type. The most favored site is the parotid (86%), occasionally the submaxillary gland, minor salivary glands.[1] ACC is a neoplastic growt...

Myoepitheliomas account for less than 1% of all salivary gland tumors and mostly occur in the parotid gland and palate. A 58-year old male patient reported to the Outpatient Department of PMS College of Dental Science and Research (Kerala, India) with a slow growing painless swelling on the palate for 4 years. Pleomorphic adenoma, basal cell adenoma, myoepithelioma, cyst adenoma, lipoma, neurof...

AIMS To review definitive histological diagnoses of patients with great salivary gland tumors with focus on the relatively high incidence of pediatric pilomatrixomas. The authors focus on clinical investigation, imaging methods and fine needle aspiration cytology of pilomatrixomas. METHODS We treated 12 children with great salivary gland masses aged from 6 months to 18 years from 1995 to 2010...

OBJECTIVES The aim of this study was to evaluate the diagnostic accuracy and efficacy of Fine needle aspiration cytology (FNAC) in various salivary gland swellings. MATERIALS AND METHODS This retrospective study was performed at Kathmandu Medical College Teaching Hospital (KMCTH) from January 2004- December 2006.During this period a total of 978 FNAC's were done out of which 40 FNAC's were on...

Primary pulmonary salivary gland-type tumors are rare neoplasms arising from the seromucinous submucosal glands of the lower respiratory tract (LRT), the most common of which are mucoepidermoid carcinoma (MEC) and adenoid cystic carcinoma. They are morphologically indistinguishable from their salivary gland counterpart and recognizing them is a challenge, especially on cytological specimens. We...

Most salivary gland tumors are benign, malignant lesions accounting for 15-30% of the total. The most frequent site of salivary gland neoplasms is the parotid gland (80% of all cases). We present a case of malignant fibrohistiocytoma with atypical features due to its location (in the parotid region), size and rapid growth. Generally, this type of tumor arises in the lower limbs and in the abdom...

The aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. The rats were treated with thymol at dose of 50 mg/Kg before exposure to radiation at dose 15Gy. Salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was ca...