Significant increase in the salivary gland weight was observed after exposure to single therapeutic dose of 3.7 MBq of 131I in mice. Pre-supplementation of antioxidants, O. sanctum leaf extract, turmeric extract and vitamin E for 15 days before 131I exposure demonstrated significant reduction in the salivary gland weight. No major histopathological changes were observed in the salivary gland of...

BACKGROUND Locoregionally advanced salivary gland malignancies have a poor prognosis despite aggressive therapy. Herein we report our experience in treating high-risk salivary gland malignancies with concurrent chemoradiotherapy (CRT). METHODS Medical records of 15 patients with salivary gland malignancies treated with CRT at our institution between 1997 and 2010 were analyzed. RESULTS All ...

The human kallikrein 5 protein (hK5) is expressed in many normal tissues, most notably in skin, breast, salivary gland and esophagus. It has also been shown to be a potential biomarker for breast, ovarian and testicular cancer. Human kallikrein 3 (hK3; prostate-specific antigen) is the most useful marker for adenocarcinoma of the prostate gland. The aim of this study was to determine whether hK...

OBJECTIVE The commonly associated aetiology of salivary gland inflammation and salivary hypofunction has led to the widely held belief that inflammation causes salivary gland hypofunction. Indeed, our own recent study seemed to support this contention. Here, we tested the hypothesis that, in an acute duct ligation model, eliminating inflammation the submandibular gland would recover normal func...

Salivary gland proteins from female Aedes aegypti mosquito were extracted and analyzed on high-resolution mass spectrometry. Proteomic data was analysed using two search algorithms SEQUEST and Mascot, which results in acquisition of 83,836 spectra which were assigned to 5417 peptides belonging to 1208 proteins.These proteins were then assigned molecular functions and further analysis revealed b...

Salivary gland hypofunction, also known as xerostomia, occurs as a result of radiation therapy for head cancer, Sjögren's syndrome or aging, and can cause a variety of critical oral health issues, including dental decay, bacterial infection, mastication dysfunction, swallowing dysfunction and reduced quality of life. Here we demonstrate the full functional regeneration of a salivary gland that ...

PURPOSE The purpose of this study was to assess cone-beam computed (CBCT) sialography imaging in the detection of different changes associated with lesions of salivary glands. MATERIALS AND METHODS This study consisted of 8 cases with signs and symptoms from salivary gland lesions. Conventional sialography using digital panoramic and lateral oblique radiographs and CBCT sialography were perfo...

background and aims. mast cells are one of the characteristic factors in angiogenesis, growth, and metastatic spread of tumors. the distribution and significance of mast cells in many tumors have been demonstrated. however, few studies have evaluated mast cell infiltration in salivary gland tumors. in this study, mast cell counts were evaluated in benign and malignant salivary gland tumors. mat...

background: sand fly saliva helps parasite establishment and induce immune responses in vertebrate hosts. in the current study, we investigated the modulation of phlebotomus papatasi salivary gland antigen expression by sea­sonal and biological factors. methods: sand flies were grouped according to physiological stages such as unfed, fed, semi-gravid, gravid, parous, nulliparous, infected or no...

background and aims. although salivary gland tumors are not very common, early diagnosis and treatment is crucial because of their proximity to vital organs, and therefore, determining the efficacy of new imaging procedures becomes important. this study aimed to evaluate the efficacy of magnetic resonance imaging (mri) and color doppler ultrasonography parameters in the diagnosis and differenti...