The effect and related mechanisms of miR-127-5p on the cartilage differentiation of rat bone marrow mesenchymal stem cells (BMSCs) was investigated. Rat BMSCs were generated and transfected with miR-127-5p, RT-PCR and Safranin O staining were used to detect the effect of miR-127-5p on the cartilage differentiation of rat BMSCs. Western blot analysis was used to detect the related mechanisms of ...

Bone marrow-stimulating techniques such as microfracture and subchondral drilling are valuable treatments for full-thickness cartilage defects. However, marrow stimulation-derived reparative tissues are not histologically well-documented in human osteoarthritis. We retrospectively investigated cartilage repairs after marrow stimulation for the treatment of large cartilage defects in osteoarthri...

introduction: citrus fruits, which belong to the family of rutaceae are one of the main fruit tree crops grown throughout the world. although sweet orange (citrus sinensis) is the major fruit in this group accounting for about 70% of citrus output.citrus fruits are well – appreciated fortheir refreshing juice and health benefits.the health benefits of citrus fruits are linked to the high amount...

Agent Orange is at the core of an ongoing controversy involving veterans organizations that want the Federal govenment to complete a study intended to examine possible lasting health effects of exposure to this herbicide during the Vietnam War. Many Vietnam veterans are quite concerned that various health problems they have suffered may be associated with exposure to Agent Orange in Vietnam. Th...

Orange peel extract solution contains mucilage flavor and three types of glycosides. Limonene is one of the terpenoides in some vegetables, fruits and food; that plays as an antioxidant in juice. As it has anti-microorganism effects on some bacteria, we carried out the antifungal effects of limonene versus orange extract. In the present study the effects of orange extract and two types of limon...