Saffron (Croucus sativus L) has been used traditionally as a spice for flavoring and coloring preparations. The aim of the present study is to evaluate the effect of saffron on some neurotransmitter content in the different brain regions, i.e. cerebellum, brainstem, striatum, cerebral cortex, hypothalamus and hippocampus. The daily (i.p.) administration of saffron extract (60mg/kg) for four wee...

Crocus sativus L. belonging to the family Iridaceae (syn - kesar) comprises the dried red stigma and is widely cultivated in Iran and other countries such as India and Greece. Saffron contains more than 150 volatile and aroma-yielding compounds mainly terpenes, terpene alcohol, and their esters. The bitter taste and an iodoform or hay-like fragrance are caused by chemicals picrocrocin and safra...

Traditional knowledge can be used as a source for development of new medicines. In the present study, we compare the data on saffron in Razi's Al-Hawi book with modern scientific studies. A computerized search of published articles was performed using MEDLINE, Scopus as well as native references. The search terms used were saffron, Crocus sativus, crocetin, crocin, safranal, Razi, and Al-Hawi. ...

Generation of volatiles by thermal treatments has been studied in saffron spice for two reasons: (a) to determine volatile profile changes during simulated aging processes and (b) to study the volatile generation pathway. During the aging process, while the amounts of C10 compounds such as safranal and HTCC increase, the amounts of C9 compounds such as isophorone and 2,6,6-trimethylcyclohexane-...

Saffron (Crocus sativus L.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. The pharmacological properties of saffron and its main constituents, crocin and safranal have been evaluated using different in vivo and in vitro models. Additionally, other lines of studies have found toxicological effects of saffron. How...

Background & Aim: Saffron is one of the expensive spices known since antiquity for its color, flavor and medicinal properties. Saffron is the dried stigma of crocus sativus plant. The three basic components of the stigma on which the qualitative characteristics of Saffron depend are crocin (color), picrocrocin (taste), and safranal (aroma). The quality of saffron is a ...

background: saffron (crocus satious l.) provides a variety of promising preventive and therapeutic effects with non-considerable side effects. objective: based on our knowledge, this is the first study that simultaneously has reviewed the effect of saffron extract and its constituents on the factors associated with neuropsychological, cardiovascular, and gastrointestinal tract diseases. methods...