Left ventricular angiograms of 16 patients with mitral stenosis and 18 normal subjects were digitised frame by frame to study regional diastolic wall motion. Left ventricular cavity volume and its rate of change were derived, and plots constructed to show regional wall motion throughout the cardiac cycle. Patients with mitral stenosis had a significantly reduced peak filling rate of 380±170 ml/...

The teichoic acids in and beneath the walls of staphylococci are particularly interesting, not only with regard to structure and function but also because of their serological properties. The groupantigenic polysaceharide A from Staphylococcus aureus is indistinguishable from the wall teichoic acid from that organism, and a similar preparation from S. albi4s strains is serologically indistingui...

Staphylococcus aureus has long been recognized as a major cause of hospital-acquired infection. Over the last decade, methicillin-resistant S. aureus (MRSA) strains have become endemic in hospitals worldwide, including in the UK. Accordingly, the frequency of MRSA isolation has increased dramatically. Glycopeptides, such as vancomycin, are often the therapeutic drugs of choice for serious MRSA ...

© 2008 Association médicale canadienne S excision of malignant chest wall tumours may be either palliative or curative. We present a case of a myxoid chondrosarcoma that arose from the lateral chest wall, invaded the right hemidiaphragm and was compressing the right hepatic lobe. An extensive resection of the right lower quadrant of the chest wall and a wide part of the right hemidiaphragm was ...

To determine the chest wall movement of each patient during deep inspiratory breath hold (DIBH) and expiratory breath hold (EBH) in postoperative breast cancer patients. Postoperative breast cancer patients who underwent CT simulation for 3D radiotherapy treatment planning during December 2012 to November 2013 were included. Before scanning the radio-opaque wire was placed on the surface for br...

A crude cell wall fraction of Listeria monocytogenes was prepared by sonic disruption and differential centrifugation of viable, washed cultures. When injected into mice, this sterile, crude cell wall fraction protected mice against an intraperitoneal challenge with 18 to 85 50% mean lethal dose of L. monocytogenes. Resistance was greatly enhanced when bacterial endotoxin (lipopolysaccharide) w...

Several epidemiological studies have suggested a modulatory effect of dietary folate intake on the risk of colorectal cancer. The molecular basis for this inverse association is not clearly understood, but may involve alterations in DNA methylation. In this study, we examined the levels of methylation intermediates [S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH)] and of global DNA ...

We identified a gene for β-1,3-glucan synthesis (GBG1), a nonessential gene whose disruption alters cell wall synthesis enzyme activities and cell wall composition. This gene was cloned by functional complementation of defects in β-1,3-glucan synthase activity of the the previously isolated Saccharomyces cerevisiae mutant LP0353, which displays a number of cell wall defects at restrictive tempe...

Valid identification of the vulnerable asymptomatic carotid atherosclerosis remains a crucial clinical issue. In this study, texture differences were estimated along the atherosclerotic arterial wall, namely at the plaque, the wall adjacent to it and the plaque shoulder, i.e. the boundary between wall and plaque, in an attempt to reveal morphological phenomena, representative of the high stenos...

We studied the impact of wall strain and surrounding pressure on the onset of airflow limitation in a thin-walled "floppy" tube model. A vacuum source-generated steady-state (baseline) airflow (0-350 ml/s) through a thin-walled latex tube (length 80 mm, wall thickness 0.23 mm) enclosed within a rigid, sealed, air-filled, cylindrical chamber while upstream minus downstream pressure, chamber pres...