background: paget's disease is a focal bone disorder manifested as bone overgrowth and disrupted bone integrity as a result of accelerated bone remodelling rate. rarely, paget's disease of the base of the skull results in hydrocephalic dementia, and the triad of normal pressure hydrocephalus syndrome is a much more scarce entity. case report: herein, we report an elderly woman who presented in ...

abstract   backgrounds: pott's disease is a rare form of extrapulmonary tuberculosis, and   presents with several clinical patterns. delay in diagnosis and management may   cause serious complications. we conducted a retrospective study between 1991-   2006 to evaluate clinical presentation, radiologic and laboratory findings, and therapeutic   approaches to spinal tuberculosis.   methods:...

introduction: one of the most common syndromes in parkinson's disease (pd) is rigidity. currently, an index is used to evaluate the level of pd by the clinical measurement of rigidity in the upper extremity. the index uses a subjective method called unified parkinson's disease rating system (updrs). the subjective nature of this method makes the influence of physician in the measureme...

background: marjolin's ulcer is a rare, aggressive condition that arises on chronic skin lesions and diseases. in this article, we will report 83 cases of this disease. methods: retrospectively, we retrieved 83 records of patients with cancer arising from chronic skin conditions. data concerning demography, type of original skin insult, time interval between original lesion and cancer, cancer h...

a 33-year-old female-a known case of behcet's disease- was admitted to the hospital due to fever, dyspnea and hemoptysis. one week before admission, she had developed right leg swelling. the history suggested either deep vein thrombosis (dvt) and pulmonary emboli or pulmonary artery vasculitis. diagnostic tests were requested and the necessary treatment was started accordingly

Parkinson’s disease is the second most common age associated neuron degenerative disorder in developed societies. With the prevalence ranging from 41 per 100000 in the fourth decade of life to over 1900 per 100000 in people over 80 years of age.it characterized clinically by resting tremor, slowness of movement, rigidity and postural instability in the result of progressive loss of dopami...

background and objective: alzheimer’s disease (ad) is a neurodegenerative disorder specified by deposition of b-amyloid (ab) and neuronal loss that leads to learning and memory disturbances. one of the most important causes of ad is glutamate-dependent excitotoxicity in brain regions that is vulnerable to ad. according to previous reported results, it was revealed that riluzole, as a glutamate ...

introduction: ulcerative colitis (uc) and crohn's disease (cd) are chronic inflammatory bowel diseases (ibd) with uncertain etiology thought to be triggered by interactions between various environmental, genetic and immunologic factors. role of different factors in ibd are controversial. materials and methods: the aim of this study is to determine the possible risk factors in a group of iranian...