Large open surgical approaches are being extensively replaced by endoscopic and robotic techniques. Yet, these developments have not been paralleled by the necessary improvements in tissue adaptation, fusion or fixation. In order to advance the surgical area to a higher and improved level, adequate tissue fusion methods need to be designed. We therefore developed a sutureless electromagnetic ti...

Single-molecule techniques provide opportunities for molecularly precise imaging, manipulation, assembly and biophysical studies. Owing to the kinetics of bond rupture processes, rapid single-molecule measurements can reveal novel bond rupture mechanisms, probe single-molecule events with short lifetimes and enhance the interaction forces supplied by single molecules. Rapid measurements will al...

[1] We relate seismologically observable parameters such as radiated energy, seismic moment, rupture area, and rupture speed to the dynamics of faulting. To achieve this objective, we computed the radiated energy for 23 subduction zone earthquakes recorded between 1992 and 2001; most of these earthquakes have a magnitude Mw > 7.5, but we also included some smaller (Mw 6.7) well-studied subducti...

Single-molecule pulling experiments on unstructured proteins linked to neurodegenerative diseases have measured rupture forces comparable to those for stable folded proteins. To investigate the structural mechanisms of this unexpected force resistance, we perform pulling simulations of the amyloid β-peptide (Aβ) and α-synuclein (αS), starting from simulated conformational ensembles for the free...

Liquid crystal elastomer (LCE) has been recently explored extensively to make diverse active structures and devices. Depending on synthetic process, LCE can be made either polydomain or monodomain when ambient temperature is below isotropic clearing temperature. In the applications, LCE may be subjected to large mechanical stretch or force and break apart. The capability of predicting the ruptu...

We probe the dynamic strength of multiple biotin-streptavidin adhesion bonds under linear loading using the biomembrane force probe setup for dynamic force spectroscopy. Measured rupture force histograms are compared to results from a master equation model for the stochastic dynamics of bond rupture under load. This allows us to extract the distribution of the number of initially closed bonds. ...

an energy based damage index based on a new nonlinear finite element (fe) approach applicable to rc structures subjected to cyclic, earthquake or monotonic loading is proposed. the proposed method is based on the evaluation of nonlinear local degradation of materials and taking into account of the pseudo-plastic hinge produced in the critical sections of the structure. a computer program is dev...

this paper focuses on the optimization of initiating dimensions of groove bearing in association with de- sired design of vehicle’s front structure which is made up of low carbon steels in the case of frontal collision. axial bearing analysis is done numerically using nonlinear finite element code ls-dyna. in this analysis, changes of two main parameters including measure of energy absorption o...

The determination of mechanical properties unshelled Moringa oleifera seeds was studied under compression test at varying orientations and moisture contents for postharvest equipment design. A completely randomized block design (CRBD) applied in designing the experiment. impact content levels (10.25, 17.33, 24.47, 32.34% dry basis) on force bio-yield rupture, deformation, energy crushing streng...