Performing optimisation and scale-up studies of crystallisation systems requires accurate and computationally efficient mathematical models. The assumption of the ideal mixing conditions in batch reactors typically produce inaccurate results while the computational expense of CFD models is still prohibitively high. Therefore, in this work, a new intermediary approach is proposed that takes into...

T he growth of business enterprises and the Internet's emergence as a data processing medium have caused server-centric applications to proliferate. Data-centric services , such as file servers, Web portals, and transaction-processing systems have become commonplace in large corporations, smaller businesses, and academic institutions. Further, search engines such as Google and e-mail services l...

We analyze the observability properties of the kinematic model of an autonomous underwater vehicle (AUV) moving in 3D, under the influence of ocean currents, using range and depth measurements. The results obtained shed light into the types of trajectories that an AUV may be requested to undergo in order to ensure observability, which is a crucial step in the design of single or multiple beacon...

Single particle imaging is a method for studying the mobility and associations of receptors in cell surfaces of living cells. In principle, it involves labeling or tagging receptors with small fluorescent particles and imaging with a highly sensitive imaging system that allows resolution at nanometer scale. The fluorescent particle can be either unconjugated or conjugated to, for example, an an...

We analyze the observability properties of the kinematic model of an autonomous underwater vehicle (AUV) moving in 3D, under the influence of ocean currents, using range and depth measurements. The results obtained shed light into the types of trajectories that an AUV may be requested to undergo in order to ensure observability, which is a crucial step in the design of single or multiple beacon...

Objectives: Biochemical joint tissue changes are associated with the development of posttraumatic osteoarthritis (PTOA). Serial assessments serum biomarkers related to cartilage degradation predictive symptomatic progression idiopathic knee OA but have not been explored in patients PTOA following anterior cruciate ligament (ACL) injury. Both and synovial biomarker profiles inflammation post-ACL...

We consider the problem of sampling a sequence from a discrete random probability measure (RPM) with countable support, under (probabilistic) constraints of finite memory and computation. A canonical example is sampling from the Dirichlet Process, which can be accomplished using its stick-breaking representation and lazy initialization of its atoms. We show that efficiently lazy initialization ...

Efficiently installing and configuring large sets of computer systems is an important concern for system and cluster administrators. Current solutions usually follow one of the two approaches: an image-based install or a metadata-based custom install. Both approaches limit the opportunities for optimizing the installation time by coupling the system specification with the installation technique...

The Odyssey IV class AUV was designed to fill the evolving needs of research and industry for a deep rated (6000 meter) vehicle, which is capable of both efficient cruising and precise hovering. This AUV is powerful enough to reject currents typical in the open ocean environment and yet small enough to be deployed from a small fishing boat. The thruster layout, two vectored side thrusters and t...

The application of a stochastic optimiser to two problems in engineering design is presented. The benefits of using such an optimiser in conjunction with a calculus based method are discussed, and its ability to succeed in non-linear and discontinuous design spaces is shown in light of two aerospace design optimisation problems: the design of quiet and efficient propellers and the design of a m...