In a human cancer cell line, we previously found a mutation in codon 322 of the extracellular signal-regulated kinase (ERK2E322K), the protein showed a faster migration when compared to wild-type in SDS-PAGE and constitutive phosphorylation. However, the reason for the faster migration, and the biochemical and biological properties of the mutation is unknown. In this study, we report that the a...

We consider a class of nonlinear Schrödinger equation in four and five space dimensions with an attractive potential. The nonlinearity is local but rather general encompassing for the first time both subcritical and supercritical (in L) nonlinearities. We show that the center manifold formed by localized in space periodic in time solutions (bound states) is an attractor for all solutions with a...

The objective of this work was to introduce a novel method for refining the solidification microstructure. Traditional casting usually solidifies one homogeneous liquid by removing heat from liquid surface, by which the microstructure solely depends on the heat removal rate for the given alloy composition. The newly developed multi-liquid composite simultaneous casting concept raises an alterna...

Although sensory problems, including tactile hypersensitivity and hyposensitivity (DSM-5) are commonly associated with autism, there is a dearth of systematic and rigorous research in this domain. Here, we report findings from a psychophysical experiment that explored differences in tactile perception between individuals with autism and typically developing control participants, who, using thei...

he objective of this work was to evaluate the surface roughness changes of three current resin cements after tooth brushing simulation, as well as discuss its relation with scanning electron microscopic observations. The materials employed were Enforce Sure Cure (Dentsply), Rely X (3M-ESPE) and Variolink II (Vivadent). They were subjected to brushing abrasion (100,000 strokes for each specimen)...

Graffiti can sometimes be a problem when put in an inappropriate place. We looked at a means to prevent such inconvenience. In this work, we explore the possibility of developing surfaces with controlled wettability. If the paint does not spread, the graffiti does not stay. Here, the synthesis and electrodeposition of original 3,4-ethylenedioxythiophene (EDOT) with perfluorinated nucleolipids (...

have been recorded. The boy was quite well up to about four months ago, when his mother noticed some spots about his neck, which had since extended from above downwards, following the course of the cutaneous spinal nerves. In the cases previously recorded the spots were observed on only one side of the body. In this instance they appeared on both sides. The groups of papillae approached in char...

In geographic information systems and in the production of digital maps for small devices with restricted computational resources one often wants to round coordinates to a rougher grid. This removes unnecessary detail and reduces space consumption as well as computation time. This process is called snapping to the grid and has been investigated thoroughly from a computational-geometry perspecti...

Scattering effects from microtopographic surface roughness are merely nonparaxial diffraction phenomena resulting from random phase variations in the reflected or transmitted wavefront. Rayleigh-Rice, Beckmann-Kirchhoff. or Harvey-Shack surface scatter theories are commonly used to predict surface scatter effects. Smooth-surface and/or paraxial approximations have severely limited the range of ...

Onsager conjectured that weak solutions of the Euler equations for incompressible fluids in R conserve energy only if they have a certain minimal smoothness, (of order of 1/3 fractional derivatives) and that they dissipate energy if they are rougher. In this paper we prove that energy is conserved for velocities in the function space B 3,c(N). We show that this space is sharp in a natural sense...