the first step in mining activities is rock excavation in both mine development and production. constant pressure for cost reduction and creating an improved/safe work environment for personnel has naturally resulted in increased use of mechanical excavation systems in many mining operations. also, mechanical excavation and mining is more compatible with automation, meaning possibility of reduc...

Despite evidence that weathering plays a role in forming intertidal, estuarine, and fluvial rock platforms, many publications uncritically refer to “wave-cut” or “stream-cut” rock platforms. The alternative explanations of chemical weathering and physical water erosion of rock platforms have been debated since 1839. Our new approach to this long-standing problem introduces data from fluvial as ...

Peroxisome proliferator-activated receptor-γ (PPARγ) and Rho-kinase (ROCK) regulate smooth muscle cell (SMC) proliferation and contribute to vascular remodeling in adult pulmonary hypertension. Whether these pathways interact to contribute to the development of vascular remodeling in persistent pulmonary hypertension of the newborn (PPHN) remains unknown. We hypothesized that ROCK-PPARγ interac...

Rock physics modeling aims to provide a link between rock properties, such as porosity, lithology, and fluid saturation, and elastic attributes, such as velocities or impedances. These models are then used in quantitative seismic interpretation and reservoir characterization. However, most of the geophysical measurements are uncertain; therefore, rock physics equations must be combined with mat...

Rho-associated kinase (ROCK) I mediates signaling from Rho to the actin cytoskeleton. To investigate the in vivo functions of ROCK-I, we generated ROCK-I-deficient mice. Loss of ROCK-I resulted in failure of eyelid closure and closure of the ventral body wall, which gave rise to the eyes open at birth and omphalocele phenotypes in neonates. Most ROCK-I(-/-) mice died soon after birth as a resul...

27 Using projective and objective measures, effects of rock music on emotion were investigated. Sixty students were randomly assigned to three conditions: hard rock, soft rock, and no music. One group listened to hard rock music while taking a projective test with five ink blots and an objective test with an Emotional Assessment Scale (EAS). The same procedure was used for the second group whil...

The homologous mammalian rho kinases (ROCK I and II) are assumed to be functionally redundant, based largely on kinase construct overexpression. As downstream effectors of Rho GTPases, their major substrates are myosin light chain and myosin phosphatase. Both kinases are implicated in microfilament bundle assembly and smooth muscle contractility. Here, analysis of fibroblast adhesion to fibrone...

The evaluation of local stability of the tunnel surrounding rock mass with weak rock layer is very important for the economy and security of the tunnel construction. Based on the rock tunnel geological conditions in the construction, the finite element model of the tunnel surrounding rock mass stability analysis with weak rock layer is established in the article by selecting the ABAQUS program ...

In terms of target detection and classification, scattering from exposed rock on the seafloor, (i.e., individual rocks and rock outcrops) presents some of the most difficult challenges for modern MCM and ASW sonar systems in shallow water. Work on characterizing, modeling and simulating mean levels and other statistical measures of acoustic scattering from rocks and rock outcrops is therefore c...

Axonal injury due to prostatectomy leads to Wallerian degeneration of the cavernous nerve (CN) and erectile dysfunction (ED). Return of potency is dependent on axonal regeneration and reinnervation of the penis. Following CN injury (CNI), RhoA and Rho-associated protein kinase (ROCK) increase in penile endothelial and smooth muscle cells. Previous studies indicate that nerve regeneration is ham...