1. Transport by the gill-like opercular epithelium of the teleost, Fundulus heteroclitus, was affected by pardaxin, a protein that is toxic to fish, isolated from the Red Sea flatfish Pardachirus marmoratus. 2. Administration of pardaxin to the mucosal (seawater) side of the isolated short-circuited opercular epithelium, caused a transient stimulation of the active transport of ions (Isc), foll...

The effect of chronic activation or inhibition of central ANG II receptors on cardiac baroreflex function in conscious normotensive rabbits was examined. Animals received a fourth ventricular (4V) infusion of ANG II (30 and 100 ng/h), losartan (3 and 30 microg/h), or Ringer solution (2 microl/h) for 2 wk. After 1 and 2 wk, ANG II (100 ng/h) decreased cardiac baroreflex gain by 20 and 37%, respe...

tuftsin activity in the sera of patients was also evaluated. Fifteen patients were included in this study: six with myelofibrosis, seven with acute granulocytic leukemia, and two with myelomonocytic leukemia. In all six cases of myelofibrosis, the polymorphonuclear cells showed a normal level of basal phagocytosis in Krebs-Ringer phosphate glucose medium. Five of seven cases of acute granulocyt...

Rapid axonal depolarization follows the elevation of [K+]o in the Ringer bathing the surfaces of the connectives of both intact and desheathed cerebrovisceral connectives of Anodonta cygnea. Potassium movements between the blood or medium bathing the surface of the connectives and the axonal membranes can be accounted for in terms of a first-order diffusion process. No visible structural barrie...

Blood glucose concentration, pH and standard bicarbonate concentration were measured in 70 anaesthetized children aged between 2 weeks and 22 months before and following surgery. The duration of starvation varied between 4 and 14 h (mean 5.8 h). The lowest blood-glucose concentration before operation was 2.9 mmol litre-1 (53 mg dl-1). Preoperative blood-glucose concentrations were not influence...

The in vitro transfer of DDT through various media to rat adipose tissue was examined. About 15% of DDT was transferred through Krebs-Ringer solution to the tissue slices after 2-hr incubation at 37 degrees C. The addition of albumin accelerated the transfer of DDT proportionally to the concentrations up to 1.0%. Hemoglobin and gamma-globulin showed a lesser accelerating activity, but protamine...

1. Controversy on Spindle potential Katz l ) has recorded a slow depolarizing potential from the sensory nerve terminal of the frog IVth toe muscle during stretch, and has termed this the 'spindle potential'. Since the amplitude of the spindle potential changed almost in parallel with the muscle tension 1) and also with the rate of afferent discharges,2,3) the spindle potential was considered t...