In some registration applications additional user knowledge is available, which can improve and accelerate the registration process, especially for non-rigid registration. This is particularly important in the transfer of pre-operative plans to the operating room, e.g. for navigation. In case of tubular structures, such as vessels, a geometric representation can be extracted via segmentation an...

Our aim is to develop methodologies for the determination of ADC, suitable for use in patient management and drug trials. In this paper we demonstrate improvements in ADC measurement which at the same time maintain the biological structures essential for analysis of tissue heterogeneity. Two motion correction methods are compared, one based upon non-rigid registration using freely available ope...

In this paper, a new framework of nonlocal deformation in non-rigid image registration is presented. It is well known that many non-rigid image registration techniques may lead to unsteady deformation (e.g. not one to one) if the dissimilarity between the reference and template images is too large. We present a novel variational framework of the total fractional-order variation to derive the un...

We present a new method for rigid registration of CT scans in Radon space. The inputs are the two 3D Radon transforms of the CT scans, one densely sampled and the other sparsely sampled. The output s the rigid transformation that best matches them. The algorithm starts by finding the best matching between each direction vector in the sparse transform and the corresponding direction vector in th...

In medical imaging, registration is used to combine images containing information from different modalities or to track treatment effects over time in individual patients. Most registration software packages do not provide an easy-to-use interface that facilitates the use of registration. 2D visualization techniques are often used for visualizing 3D datasets. RegistrationShop was developed to i...

Several recent studies demonstrate the potential of using tubular structures such as vessels as a basis for image registration. In this paper, we present a novel technique for the deformable registration of tubular structures. Our approach aligns tubular models, e.g. vessels of an organ, with an image by combining both rigid and non-rigid transformations in a hierarchical manner. The physical s...

We present a robust and efficient algorithm for the pairwise non-rigid registration of partially overlapping 3D surfaces. Our approach treats non-rigid registration as an optimization problem and solves it by alternating between correspondence and deformation optimization. Assuming approximately isometric deformations, robust correspondences are generated using a pruning mechanism based on geod...

Many neuroanatomy studies rely on brain tissue segmentations of magnetic resonance images (MRI). We present a segmentation tool, which performs this task automatically by analyzing the MRIs as well as tissue specific spatial priors. The priors are aligned to the patient through a non-rigid registration method. The segmentation itself is parameterized by an XML file making the approach easily ad...

Assume that only partial knowledge about a non-rigid registration is given so that certain points, curves, or surfaces in one 3D image map to certain certain points, curves, or surfaces in another 3D image. We are facing the aperture problem because along the curves and surfaces, point correspondences are not given. We will advocate the viewpoint that the aperture and the 3D interpolation probl...

PURPOSE Registration is one of the key technical components in an image-guided navigation system. A large number of 2D/3D registration algorithms have been previously proposed, but have not been able to transition into clinical practice. The authors identify the primary reason for the lack of adoption with the prerequisite for a sufficiently accurate initial transformation, mean target registra...