نتایج جستجو برای: rhg csf
تعداد نتایج: 28517 فیلتر نتایج به سال:
Patients with severe aplastic anemia (SAA) and a neutrophil (PMN) count of less than 0.5 x 109/L are exposed to a high risk of early mortality when treated with antilymphocyte globulin (ALG) and steroids, with the major problem being infectious complications. The addition of human recombinant granulocyte colony-stimulating factor (rhG-CSF) to ALG may reduce early mortality by improving neutroph...
Five syngeneic transplants were performed in four patients following myeloablative therapy using unmodified peripheral blood mononuclear cells (PBMCs) collected after the administration of recombinant human granulocyte colony stimulating factor (rhG-CSF) to normal donors. The only toxicity experienced by the four normal donors was bone pain. Four patients received two collections of PBMCs, and ...
phadenopathy. Laboratory studies revealed a hematocrit of 18.3%, platelet count 118000/mm3, and leukocyte count of 5200/mm3 with 81% lymphoblasts, 1% myelocytes, 4% neutrophils and 14% lymphocytes. The bone marrow smear showed 95% blast cells. Intravenous piperacillin and gentamicin therapy was started on an empirical basis. After 10 days without response to the antibiotic regimen, he received ...
Peripheral blood stem cells (PBSCs) are widely used in autologous transplantation because of ease of collection and rapid hematopoietic reconstitution. However, PBSCs have rarely been used for allogeneic transplantation because of concerns about donor toxicities from cytokine administration and the theoretical increased risk of graft-versus-hostdisease (GVHD) from the large number of T cells in...
Because of the similar phenotypes they generate and their proximate reported locations on Chromosome 7, we tested the recessive retarded hair growth (rhg) and frizzy (fr) mouse mutations for allelism, but found instead that these defects complement. To discover the molecular basis of rhg, we analyzed a large intraspecific backcross panel that segregated for rhg and restricted this locus to a 0....
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