The hepatotoxicity of some Chinese herbs has been a cause for concern in recent years. However, some herbs, such as rhubarb, have been documented as having both therapeutic and toxic effects on the liver, leading to the complex problem of distinguishing the benefits from the risks of using this herb. To comparatively analyze the dose-response relationship between rhubarb and hepatic health, we ...

tosus. Ann Rheum Dis 2005;64:947–50. 9. Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315–24. 10. Svensson B, Schaufelberger C, Teleman A, Theander J. Remission and response to early treatment of RA assessed by the Disease Activity Score. BARFOT study group. Better Anti-rh...

DT. Factors predicting response to treatment in rheumatoid arthritis: the importance of disease duration. Arthritis Rheum 2000;43:22–9. 15 Kroot EJ, van Leeuwen MA, van Rijswijk MH, Prevoo ML et al. No increased mortality in patients with rheumatoid arthritis: up to 10 years of follow up from disease onset. Ann Rheum Dis 2000;59:954–8. 16 Nell VP, Machold KP, Eberl G, Stamm TA et al. Benefit of...

.37. Boileau C, Martel-Pelletier J, Brunet J, et al. Oral treatment with PD-0200347, anα2δ ligand, reduces the development ofexperimental osteoarthritis by inhibiting metalloproteinases and inducible nitric oxide synthase gene expression and synthesis in cartilage chondrocytes. Arthritis Rheum. 2005 Feb;52(2):488-500.38. Pelletier JP, Lascau-Coman V, Jovanovic D, et al. Selectiv...

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view of scoring methods, their reliability and applicability. Baillieres Clin Rheumatol 1996;10:435–53. 2. Kuper HH, van Leeuwen MA, van Riel PL, Prevoo ML, Houtman PM, Lolkema WF, et al. Radiographic damage in large joints in early rheumatoid arthritis: relationship with radiographic damage in hands and feet, disease activity, and physical disability. Br J Rheumatol 1997;36:855–60. 3. Cranney ...

the effects of ethanolic and aqueous extracts of rheum ribs l. (rr) of the family polygonaceae was studied on serum cholesterol concentration in rabbits. to induce hypercholesterolemia, 0.5 g/kg/day of pure cholesterol powder was given orally to each rabbit for two weeks then cholesterol was halved and each group of animals was treated with a different regimen for another two weeks. both the et...

rheum turkestanicum janischew. (polygonaceae) is a plant that grows in central asia and in north-east of iran. traditionally, people use roots of r. turkestanicum as an anti-diabetic and anti-hypertensive as well as anticancer agent. in this study the cytotoxicity and apoptogenic properties of ethyl acetate (etoac), n-hexane and h2o extracts from rheum turkestanicum janischew. (polygonaceae) ro...

Objectives: Trichomoniasis is one of the most common sexually transmitted diseases in humans and is caused by the protozoan Trichomonas vaginalis. Nowadays, increasing resistance to drugs such as metronidazole resulted in many problem, so new effective remedies are needed. In this study, we evaluate constituents of essential oil and anti-trichomonas activity of Rheum ribes. Materials and Method...